Arizona at San Francisco (8:30 p.m. EST). Kurt Warner and the defending NFC champion Cardinals (8-4) can clinch their second straight NFC West title with a victory.

-Drew Brees, Saints, threw for 296 yards and three touchdowns as New Orleans remained undefeated with a 26-23 victory at Atlanta.

-Matt Schaub, Texans, had 365 yards passing and two touchdowns to lead Houston to a 34-7 win over Seattle.

-Peyton Manning, Colts, threw four touchdown passes and Indianapolis improved to 13-0 with a 28-16 win over Denver.

-Chad Henne, Dolphins, completed a team-record 17 consecutive passes during one stretch and finished 21 of 29 for 220 yards in Miami's 14-10 victory at Jacksonville.

-Eli Manning, Giants, threw for 382 yards and three TDs in a losing cause as New York lost to Philadelphia 45-38.

-Ray Rice, Ravens, ran for a career-high 166 yards and a TD, and caught four passes for 53 yards in Baltimore's 48-3 rout of Detroit.

-Jamaal Charles, Chiefs, set a career high with 143 yards rushing and a score, and also had seven receptions for 38 yards in a losing cause as Kansas City was defeated by Buffalo 16-10.

-Ryan Grant, Packers, ran for 137 yards and two touchdowns in Green Bay's 21-14 win at Chicago.

-Chris Johnson, Titans, ran for 117 yards and two touchdowns and also took a short pass 66 yards for another score as Tennessee beat St. Louis 47-7.

-Ricky Williams, Dolphins, rushed for 108 yards and a TD in Miami's 14-10 win at Jacksonville.

-Thomas Jones, Jets, had 99 yards rushing and two scores as New York cruised to a 26-3 win at Tampa Bay.

-Brandon Marshall, Broncos, set an NFL record with 21 receptions for 200 yards and two TDs in Denver's 28-16 loss at undefeated Indianapolis.

-Andre Johnson, Texans, had 11 receptions for a season-high 193 yards and two scores as Houston routed Seattle 34-7.

-Dallas Clark, Colts, caught three touchdown passes to help Indianapolis stay perfect with a 28-16 win over Denver.

-DeSean Jackson, Eagles, had 168 yards receiving and a TD on six catches in Philadelphia's 45-38 victory over the New York Giants.

-Wes Welker, Patriots, had 10 catches for 105 yards in New England's 20-10 win over Carolina.

-Reggie Bush, Saints, had two touchdown catches as New Orleans stayed undefeated with a 26-23 win at Atlanta.

-Jay Feely, Jets, made four of his five field-goal attempts in New York's 26-3 win at Tampa Bay.

-Rob Bironas, Titans, kicked four field goals with a long of 50 yards in Tennessee's 47-7 win over St. Louis.

-Rian Lindell, Bills, kicked three field goals in Buffalo's 16-10 at Kansas City.

-Brian Orakpo, Redskins, tied a franchise record with four sacks in Washington's 34-13 win at Oakland.

-Bernard Pollard, Texans, returned an interception 70 yards for a touchdown in Houston's 34-7 win over Seattle.

-Charles Woodson, Packers, had his 44th career interception in Green Bay's 21-14 victory at Chicago.

-Jonathan Vilma, Saints, came up with a crushing fourth-down hit on Jason Snelling, stopping him a yard short of the marker with just over a minute remaining to seal New Orleans' 26-23 win at Atlanta.

-Brian Dawkins, Broncos, picked off Peyton Manning twice, both on tipped balls in Denver's 28-16 loss at Indianapolis.

New Orleans and Indianapolis remained undefeated Sunday, joining five other NFL teams to reach 13-0. The Colts beat Denver 28-16, breaking NFL records for most consecutive regular-season wins (22) and most wins in a decade (114), plus wrapping up home-field advantage throughout the AFC playoffs. Indy's 114th victory of the decade broke a tie with the 1990s San Francisco 49ers and set a franchise record with its 13th consecutive home win. Meanwhile, New Orleans set a franchise record for wins in a season, clinched a first-round bye in the playoffs and moved a step closer to home-field advantage throughout the NFC playoffs.

Brandon Marshall set the NFL record with 21 catches in Denver's 28-16 loss to Indianapolis on Sunday, surpassing the mark San Francisco's Terrell Owens set on Dec. 17, 2000. Marshall finished with 200 yards and two touchdowns and bettered his team record of 18 catches, set on Sept. 14, 2008, against San Diego.

Detroit lost 48-3 at Baltimore on Sunday, increasing its road skid to 19 games, tied for fourth-longest in NFL history. The record of 24 is held by the Lions, from 2001-03. ... The Falcons (6-7) lost for the sixth time in eight games and their playoff hopes are all but over. They will need to win out to avoid extending one of the most unwanted streak in sports - Atlanta has never had consecutive winning seasons during its 44-year history. ... Jacksonville's five-game winning streak at home ended with a 14-10 loss to Miami. ... New England, which had lost three of its previous four, the Patriots' worst stretch since 2002, snapped a two-game losing streak and maintained its one-game lead in the AFC East by improving to 7-0 at home.

Indianapolis' Peyton Manning passed Warren Moon for fourth on the NFL's yards passing list. Moon had 49,325, while Manning now has 49,513. ... New Orleans' Drew Brees tied Aaron Brooks' franchise record with the 120th TD pass of his Saints career. ... Tennessee's Chris Johnson, the NFL's leading rusher, pushed him past Hall of Fame running back Earl Campbell's franchise mark of 1,981 yards from scrimmage in 1980. Johnson also has the team mark with eight straight 100-yard rushing games, breaking his tie with Campbell at seven.

New England's Wes Welker finished with 10 catches for 105 yards in a 20-10 win over Carolina, his fifth 100-yard performance of the season. He has an NFL-high 105 receptions and joined Marvin Harrison, Jerry Rice and Herman Moore as the only receivers with at least three consecutive 100-catch seasons.

DeSean Jackson scored on 72-yard punt return and a 60-yard pass in Philadelphia's 45-38 shootout victory Sunday night over the New York Giants. He has eight touchdowns of 50-plus yards this year, tying the NFL mark also held by Elroy ``Crazy Legs'' Hirsch in 1951 and Devin Hester (2007).

Vincent Fuller returned an interception 45 yards for a TD, and Keith Bulluck and Cortland Finnegan had two interceptions apiece in Tennessee's 47-7 win over St. Louis on Sunday.

Houston's Matt Schaub had 336 yards passing before halftime and finished with 365 yards and two touchdowns in the Texans' 34-7 win over Seattle on Sunday. His first-half yardage was the second-most in a first half this season in the NFL. ... Baltimore set team records in total yardage (548) and rushing touchdowns (5) and tied the franchise mark for points in a 48-3 win over Detroit.

Green Bay's Ryan Grant broke off a season-long 62-yard touchdown on the Packers' first play from scrimmage in a 21-14 win at Chicago. He ran for 137 yards and two touchdowns, including the go-ahead score in the fourth quarter after Nick Collins intercepted Jay Cutler.

Tampa Bay managed only 124 yards in a 26-3 loss to the New York Jets. They were held to 86 - 19 in the opening half - during a 24-0 home loss to the Giants in September.

Oakland committed 14 penalties and lost by at least 20 points for the fifth time this season in a 34-13 loss to Washington on Sunday. ... Cincinnati committed 11 penalties for 85 yards in a 30-10 loss at Minnesota, and Carson Palmer was held to a season-low 94 yards passing.

San Diego beat Dallas 20-17 on Sunday for its eighth straight victory, and 16th in a row in December. The Cowboys fell to 3-8 under coach Wade Phillips during the regular season's final month.

The Chargers-Cowboys game at Dallas featured the NFL debut of a 3D, in-house video, with fans given 3D glasses as they entered. It was supposed to be for the entire second half, but so few people bothered with it that the humongous video boards went back to plain ol' 2D, HD just 6:50 after the experiment began. The change drew one of the largest cheers of the game.

Dallas Cowboys linebacker DeMarcus Ware was hospitalized with a sprained neck, sustained when he slammed headfirst into a San Diego Chargers lineman in the fourth quarter of a 20-17 loss Sunday night. ... Tennessee quarterback Vince Young strained his right hamstring Sunday during the second quarter against the St. Louis Rams and didn't return as the Titans finished off a 47-7 rout. ... Oakland Raiders quarterback Bruce Gradkowski left the game against the Washington Redskins with partially sprained ligaments in both knees and was replaced by JaMarcus Russell.

``It's only going to get harder from here on out. No matter what the situation, we always feel like we have an opportunity to win. Whether it's our offense, defense or special teams, somehow we're going to find a way to win the game.'' - New Orleans quarterback Drew Brees after the Saints remained undefeated with a 26-23 win at Atlanta.

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``I'm a part of history right now, so it feels real good. It's something we can tell our kids and grandkids that we did something no one else had done. It's definitely a great accomplishment.'' - Indianapolis linebacker Clint Session after the Colts broke NFL records for most consecutive regular-season wins (22) and most wins in a decade (114) with a 28-16 win over Denver.