Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Giants | at |  | Pirates | 11:35am CT | Ray L (9-5) | Heaney L (5-9) | |
 | Orioles | at |  | Phillies | 11:35am CT | Rogers L (5-2) | Suarez L (8-5) | |
 | Twins | at |  | Tigers | 12:10pm CT | Ohi (0-2) | Flaherty R (6-11) | |
 | Guardians | at |  | Mets | 12:10pm CT | Williams R (7-4) | Peterson L (7-5) | |
 | Reds | at |  | Cubs | 1:20pm CT | Abbott L (8-2) | Horton R (6-3) | |
 | Yankees | at |  | Rangers | 1:35pm CT | Rodon L (11-7) | Leiter R (7-6) | |
 | Blue Jays | at |  | Rockies | 2:10pm CT | Gausman R (8-8) | Freeland L (2-12) | |
 | Rays | at |  | Angels | 3:07pm CT | Baz R (8-8) | Anderson L (2-7) | |
 | Cardinals | at |  | Dodgers | 3:10pm CT | Liberatore L (6-9) | Ohtani | |
 | Astros | at |  | Marlins | 3:40pm CT | Arrighetti R (1-1) | Junk R (5-2) | |
 | Athletics | at |  | Nationals | 5:45pm CT | Springs L (10-7) | Cavalli R (0-0) | |
 | Royals | at |  | Red Sox | 6:10pm CT | Wacha R (5-9) | May R (6-7) | 6:10pm |
 | Brewers | at |  | Braves | 6:15pm CT | Quintana L (8-4) | Strider R (5-8) | 6:15pm |
 | White Sox | at |  | Mariners | 8:40pm CT | Cannon R (4-8) | Kirby R (6-5) | 8:40pm |
 | Padres | at |  | Diamondbacks | 8:40pm CT | Cortes L (1-1) | DeSclafani R (1-2) | 8:40pm |
| Angels | at | | Rays | 3:00am CT | - | - | Postponed |
