Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Pirates | at |  | Orioles | 12:05pm CT | Skenes R (10-9) | Povich L (3-7) | 12:05pm |
 | Rays | at |  | White Sox | 1:10pm CT | Seymour (3-0) | Smith R (4-7) | 1:10pm |
 | Astros | at |  | Blue Jays | 2:07pm CT | Javier R (1-2) | Gausman R (8-10) | 2:07pm |
 | Nationals | at |  | Marlins | 5:40pm CT | Lord R (4-8) | Alcantara R (8-11) | 5:40pm |
 | Tigers | at |  | Yankees | 6:05pm CT | Flaherty R (7-13) | Schlittler R (2-2) | 6:05pm |
 | Mets | at |  | Phillies | 6:15pm CT | Peterson L (8-5) | Luzardo L (12-6) | 6:15pm |
 | Royals | at |  | Guardians | 6:15pm CT | Kolek (4-5) | Bibee R (9-11) | 6:15pm |
 | Angels | at |  | Mariners | 8:40pm CT | Kikuchi L (6-10) | Miller R (4-5) | 8:40pm |
 | Rockies | at |  | Padres | 8:40pm CT | Brown R (0-2) | - | 8:40pm |
