Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Tigers | at |  | Braves | 12:15pm ET | Valdez L (2-1) | Elder R (3-1) | |
 | Giants | at |  | Phillies | 12:35pm ET | Webb R (2-3) | Sanchez L (2-2) | |
 | Cardinals | at |  | Pirates | 12:35pm ET | Dobbins R (0-0) | Skenes R (4-2) | |
 | Astros | at |  | Orioles | 12:35pm ET | Lambert R (1-2) | Bassitt R (2-2) | |
 | Rockies | at |  | Reds | 12:40pm ET | Lorenzen R (2-3) | Abbott L (1-2) | |
 | Nationals | at |  | Mets | 1:10pm ET | Mikolas R (0-3) | Peralta R (1-3) | |
 | Diamondbacks | at |  | Brewers | 1:40pm ET | Soroka R (4-0) | Woodruff R (2-1) | |
 | Royals | at |  | Athletics | 3:05pm ET | Cameron L (2-1) | Springs L (3-2) | |
| Astros | at | | Orioles | 3:55pm ET | McCullers Jr. R (1-2) | Young (2-0) | |
| Giants | at | | Phillies | 5:35pm ET | - | Painter R (1-2) | 5:35pm |
 | Blue Jays | at |  | Twins | 7:40pm ET | Gausman R (2-1) | Ober R (2-1) | 7:40pm |
