Jacob deGrom took a no-hitter into the eighth inning while Josh Jung drilled a two-run homer and drove in three runs as the Texas Rangers defeated the host Baltimore Orioles 7-0 on Wednesday.

Colton Cowser's eighth-inning single marked Baltimore's only hit.

deGrom (8-2) carried a perfect game into the seventh, but Jackson Holliday worked a leadoff walk on seven pitches. With two outs in the inning, Ryan O'Hearn drew another walk.

Cowser hit deGrom's third pitch of the eighth to right field for a single, which led to a pitching change. deGrom, who improved to 4-0 in June, finished with seven strikeouts. Jonah Heim homered as the Rangers captured the rubber game of the three-game series to finish a 4-2 road trip.

Brewers 4, Pirates 2

Rookie Jacob Misiorowski threw five shutout innings to outduel 2024 National League Rookie of the Year Paul Skenes and spark Milwaukee to a victory over visiting Pittsburgh.

Misiorowski (3-0) struck out eight while scattering two singles and two walks in his third major league start. Skenes (4-7), who entered the game with a big-league-best 1.85 ERA, allowed four hits and four runs with four strikeouts and two walks over four innings.

The Brewers batted around in the second to score their runs as they strung together Joey Ortiz's RBI groundout, Eric Haase's RBI double, Sal Frelick's run-scoring fielder's choice and Christian Yelich's RBI single.

Padres 1, Nationals 0

Nick Pivetta scattered three singles and struck out a season-high-tying 10 over seven innings as San Diego registered its 13th shutout of the season to defeat visiting Washington.

For the fourth time this year, Pivetta (8-2) fired seven shutout innings. Jonathan Estrada and Adrian Morejon closed with perfect innings as the Padres allowed no runners into scoring position.

Luis Arraez's two-out single in the second drove in Tyler Wade with the game's only run. Nationals starter MacKenzie Gore (3-8), who was traded from San Diego to Washington in the 2022 Juan Soto deal, gave up one run and five hits over six innings.

Yankees 7, Reds 1

Max Fried allowed one unearned run over seven innings to help New York salvage the finale of a three-game series at Cincinnati.

Fried (10-2) struck out seven as he became the majors' first 10-game winner. Jazz Chisholm Jr. homered and Trent Grisham and Jasson Dominguez had four hits apiece for the Yankees.

Elly De La Cruz produced two hits for the Reds, who had their three-game win streak snapped. Brady Singer (7-6) yielded four runs on six hits over five innings, fanning nine.

Astros 2, Phillies 0

Jeremy Pena scored following his leadoff double in the first inning and Victor Caratini added a critical insurance run with an eighth-inning homer as Houston topped visiting Philadelphia.

Left-hander Colton Gordon (3-1) threw four innings for the Astros, and four more lefties completed the shutout. Josh Hader recorded his 21st save with a perfect ninth.

Kyle Schwarber and Brandon Marsh had two hits apiece for the Phillies, who were shut out by the Astros for the second straight night. Zack Wheeler (7-3) allowed four hits and one run in six innings.

Athletics 3, Tigers 0

Nick Kurtz hit a three-run homer, Jacob Lopez pitched seven strong innings and the visiting Athletics blanked Detroit.

Kurtz had three of the Athletics' seven hits. Lopez (2-4) allowed just three hits and walked one while striking out six in seven innings. Mason Miller got the last three outs for his 15th save.

Detroit starter Jack Flaherty (5-9), who gave up the homer, lasted six innings. He allowed five hits and four walks and struck out seven.

Marlins 8, Giants 5 (10 innings)

Rookie Heriberto Hernandez drove in four runs, including two on a double in the four-run 10th, helping visiting Miami defeat San Francisco.

Otto Lopez had three hits and three RBIs for the Marlins, who have won three in a row to match their longest winning streak of the season. Calvin Faucher (3-2) gave up two runs to blow a ninth-inning lead but still got the win.

Mike Yastrzemski led off the first inning with a homer for the Giants. Camilo Doval (3-2) allowed four runs, three earned, while getting two outs in the 10th.

White Sox 7, Diamondbacks 3

Lenyn Sosa went 3-for-4 with two homers and four RBIs and Andrew Benintendi also homered as host Chicago avoided a sweep against Arizona.

Sosa's two-run homer off Diamondbacks starter Zac Gallen (5-9) snapped a 2-2 tie in the fourth. Gallen allowed eight hits and five runs over 5 1/3 innings. Josh Naylor went 2-for-3 with a two-run homer in the first.

White Sox starter Sean Burke (4-7) posted a season-high-tying seven strikeouts in his five-inning stint while giving up five hits and two runs. Luis Robert Jr. exited due to left hamstring tightness in the first inning.

Angels 5, Red Sox 2

Yusei Kikuchi had a season-high 12 strikeouts and Travis d'Arnaud went 3-for-4 with a home run to help Los Angeles complete a three-game sweep of Boston in Anaheim, Calif.

Kikuchi (3-6) surrendered two runs (none earned) and three hits over seven innings. Jo Adell added a solo shot to open the scoring for the Angels, who won for the fourth time in five games. He and d'Arnaud drove in two runs each, and Ryan Zeferjahn secured his second save.

Trevor Story had two RBIs for the Red Sox, who lost their fifth game in a row. Richard Fitts gave up two runs on four hits while striking out six in four innings. Luis Guerrero (0-1) allowed two runs in the fifth inning.

Guardians 5, Blue Jays 4 (10 innings)

Jose Ramirez singled home the winning run in the 10th inning for his eighth career walk-off hit, giving Cleveland a victory over visiting Toronto.

Blue Jays reliever Mason Fluharty (3-2) allowed Ramirez's sharp no-out single to left. Rookie and cancer survivor Nic Enright (1-0) worked a scoreless 10th for his first win in the majors, allowing Cleveland to even the three-game series at one victory apiece.

Blue Jays starter Max Scherzer, activated earlier in the day, pitched five innings and allowed three runs on six hits. The 40-year-old struck out four and walked three over 83 pitches in his first appearance since his Toronto debut March 29. Vladimir Guerrero hit a solo home run and George Springer had two hits and two RBIs.

Mets 7, Braves 3

Juan Soto hit two homers for host New York, which ended its drought against Atlanta by cruising to a victory in the third game of a four-game series.

Soto notched the 27th multi-homer game of his career -- the most multi-homer games in MLB history for a player before turning 27. Soto broke a record he held with Jimmie Foxx. Ronny Mauricio homered among his three hits for the Mets, who entered the game 0-5 against the Braves since June 17.

Drake Baldwin homered in the fourth and Ronald Acuna Jr. had a two-run single in the ninth for the Braves. Didier Fuentes (0-2), a 20-year-old who is the youngest player in the majors, gave up six runs on eight hits over 3 1/3 innings.

Rays 3, Royals 0

Drew Rasmussen and four Tampa Bay relievers held reeling Kansas City to just three hits and sent the host club to a ninth consecutive home defeat.

Brandon Lowe, Josh Lowe and Chandler Simpson each had two hits for the Rays, whose 11 hits were all singles. Tampa Bay has won five straight road games and 24 of its past 33 contests overall. Rasmussen (7-5) yielded two hits and two walks while striking out five over five innings.

The Royals have managed just one run in the first two games of the current three-game set and have been outscored 39-12 while going 0-9 at home in June. The Royals are on their longest home losing streak since a 10-game slide in 2023.

Twins 2, Mariners 0

Joe Ryan struck out eight batters over six scoreless innings, and Minnesota held on for a win over Seattle in Minneapolis.

Kody Clemens hit a solo home run for Minnesota, which snapped a five-game losing streak and won for only the second time in its past 13 games. Willi Castro also drove in a run. Ryan (8-3) allowed three hits and no walks.

Seattle managed only three singles. Cal Raleigh, who leads the big leagues with 32 home runs, finished 0-for-4 with three strikeouts. Mariners right-hander George Kirby (1-4) limited Twins hitters to one run on three hits in six innings.

Cubs 8, Cardinals 0

Ian Happ hit a homer and drove in three runs as visiting Chicago rolled past St. Louis.

Reese McGuire hit a two-run homer and Kyle Tucker added a solo shot for the Cubs, who won for the second time in their past seven games. Michael Busch (2-for-5, two runs, RBI) and Dansby Swanson (2-for-5, two runs) also had productive games for Chicago.

Cubs starter Matthew Boyd (7-3) blanked St. Louis on three hits over six innings. Cardinals starter Erick Fedde (3-7) allowed seven runs on eight hits in 3 2/3 innings.

Dodgers 8, Rockies 1

Max Muncy hit a grand slam and drove in six runs as Los Angeles earned a rain-delayed win over Colorado in Denver.

Michael Conforto and Muncy each had a homer and a single for Los Angeles, which has won nine straight against Colorado. The Dodgers have a three-game overall winning. Starter Yoshinobu Yamamoto (7-6) tossed five shutout innings, giving up one hit and one walk while striking out six.

Tyler Freeman singled twice to extend his hitting streak to 12 games for the Rockies, who are 1-4 on their six-game homestand. Chase Dollander (2-8) was charged with three runs on three hits in 5 2/3 innings.