Baltimore Orioles middle infielder Jackson Holliday (wrist) said he will need surgery to fix his left wrist, either later this week or next week, according to Jake Rill of MLB.com. The good news is that Holliday is not dealing with a complete tear. "Hopefully just go in there and clean it up, and that'll be that," Holliday said. He has been told to expect about a 10-week recovery, so it should not impact his timeline for next season. The 22-year-old was diagnosed with a triangular fibrocartilage complex tear in his wrist. His 2026 season got off to a bad start when he needed surgery to remove a broken hamate bone in his right hand, causing him to get a late start to the campaign. The former first overall pick in 2022 was unable to fully recover, playing in just 98 games for the O's while hitting a disappointing .229/.300/.340 with a .640 OPS, seven home runs, 30 RBI, 45 runs scored, and eight stolen bases in 354 plate appearances. Holliday has yet to reach the potential that made him the first overall pick, but with a fully healthy season in 2027, he could be a deep-league sleeper at middle infield.

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Atlanta Braves outfielder Ronald Acuna Jr. (shin) is not in the team's starting lineup for Wednesday's contest at home against the visiting Cincinnati Reds, per MLB.com. Brewer Hicklen is making the start in right field for the Braves and will bat eighth against Reds left-hander Andrew Abbott. Acuna was pulled from Tuesday's game early against Cincinnati after fouling a ball off his left leg. Thankfully, X-rays came back negative, and he was diagnosed with a shin contusion. The Braves are giving Acuna a precautionary day off on Wednesday, but he could be back as soon as Thursday's series finale in Atlanta. The Braves' primary concern will be for Acuna to be ready to roll for the start of the postseason next week. The 28-year-old former MVP and five-time All-Star missed more time due to injuries in 2026, but he still managed to reach the 20-homer mark in just 104 games played while slashing .259/.352/.462 with an .814 OPS. Acuna has added 55 RBI, 20 stolen bases, and 60 runs scored. He has been seeing the ball well in September, going 25-for-74 (.338) with seven home runs, five doubles, 19 RBI, 13 runs scored, and a stolen base in 19 games.

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Boston Red Sox outfielder Ceddanne Rafaela (quadriceps) has been activated from the 10-day injured list on Wednesday and is in the starting lineup against the visiting Cleveland Guardians and left-hander Foster Griffin, starting in center field and batting sixth, according to Tim Healey of The Boston Globe. Rafaela is back for the tail end of the 2026 regular season after landing on the IL earlier this month with a strained right quad muscle. He did not go on a minor-league rehab assignment before returning, but instead took at-bats off a Trajekt machine. The Red Sox are hoping he will get enough at-bats in through the rest of the week to get him back up to speed for the start of the wild-card series next week against the division-rival New York Yankees. Rafaela is returning to a strong .282/.317/.443 slash line with a .760 OPS, 16 home runs, 70 RBI, 17 stolen bases, and 67 runs scored in his 535 at-bats this year. Boston is a much scarier team with their starting center fielder and power/speed threat back in time for the postseason.

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Boston Red Sox first baseman Willson Contreras (hand) remains out of the starting lineup for Wednesday's game at Fenway Park against the visiting Cleveland Guardians, according to The Boston Globe's Tim Healey. Nick Sogard is making another start at first base and will bat second against Guardians left-hander Foster Griffin. Contreras is now out of the starting lineup for a fifth straight game after he was hit on his right hand by a pitch last Thursday against the Texas Rangers. X-rays came back negative, but apparently the right-handed slugger is still too sore to return to action. The Red Sox would love to get Contreras back on the field by this weekend so that he can get some more at-bats heading into the big wild-card series next week against the division-rival New York Yankees. The 34-year-old Venezuelan has been great for the BoSox in 2026 with a .276/.387/.518 slash line and a career-high 27 home runs, but he has barely played in September due to injuries. Contreras also hit just .217/.330/.386 with three home runs, 12 RBI, 11 walks, and 26 strikeouts in 23 games in August. He is currently limping to the finish line.

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The Baltimore Orioles announced on Wednesday that they placed catcher Samuel Basallo (concussion) on the seven-day concussion injured list (retroactive to Sept. 22) and recalled outfielder Heston Kjerstad from Triple-A Norfolk in a corresponding move. Basallo took a foul tip off his catcher's mask in Monday's game against the Toronto Blue Jays and was pulled from the game to undergo concussion testing. The 22-year-old Dominican backstop will finish his first full season in the majors with a .222/.291/.406 slash line with a .696 OPS, 18 home runs, 54 RBI, and 40 runs scored across 112 games and 399 plate appearances. Most of the damage that Basallo did came in the first half, as he also dealt with a shoulder injury in the second half and hit just .140 (12-for-86) with a .456 OPS in 29 games since the All-Star break. The Orioles showed their trust in Basallo at this year's trade deadline by sending former first overall pick Adley Rutschman to the division-rival Boston Red Sox. If healthy in 2027, Basallo has the skills to be one of the better power-hitting catchers in the big leagues.

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The Atlanta Braves officially announced on Wednesday that they reinstated right-handed reliever Robert Suarez (elbow) from the 60-day injured list and optioned right-hander Owen Murphy to the minors in a corresponding move. After missing more than three months with inflammation in his right elbow, Suarez is back at the back end of the Braves' bullpen for the tail end of the regular season. The Braves might ease the 35-year-old veteran Venezuelan hurler back into the fold so that he is ready to roll for the postseason next month. Before his elbow injury, Suarez, a two-time All-Star who had 76 saves in the previous two seasons with the San Diego Padres, had been pitching extremely well in Atlanta. He was 4-0 with a 0.56 ERA (2.44 FIP), a 0.84 WHIP, four saves, 26 strikeouts, and six walks in 32 relief innings. Suarez's return definitely makes Atlanta's bullpen more intimidating, just in time for the postseason in October.

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Toronto Blue Jays first baseman Vladimir Guerrero Jr. (back) was a late addition to the team's starting lineup for Game 1 of Wednesday's doubleheader against the division-rival Baltimore Orioles, according to MLB.com. Guerrero made the start at first base and is hitting second against Orioles right-hander Chris Bassitt. After being pulled from Sunday's series finale against the Texas Rangers with lower-back tightness, Guerrero was not scheduled to be in Tuesday's lineup before the game was postponed due to inclement weather. He was also not initially in the starting nine for Game 1 of Wednesday's doubleheader at Camden Yards. Gurrero felt good while hitting before the game and convinced the coaching staff to let him play as Toronto's slim hopes of making the playoffs dim with each day. The 27-year-old is now just looking to finish strong after an extremely disappointing 2026 campaign. The six-time All-Star enters play Wednesday with just nine home runs in 529 at-bats while slashing .263/.336/.359.

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Baltimore Orioles right-hander Rico Garcia has been one of his team's most reliable bullpen arms in 2026, recording a 3.14 ERA, 0.98 WHIP, 68 strikeouts, and 10 saves across 66 innings (74 games). The 32-year-old has mostly functioned as a high-leverage arm in a setup role for the Orioles. However, Garcia has emerged as the team's preferred option in the ninth inning of late, recording four saves in his last six appearances. Garcia has also been extremely effective in the second half of the season, allowing just three earned runs across his last 19 appearances (16 1/3 innings). For fantasy managers in need of saves in the final week of the 2026 season, Garcia profiles as a must-roster pitcher.

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Across 40 2/3 innings (eight starts) in 2026, Detroit Tigers right-hander Jackson Jobe has recorded a 2-3 record with a 3.98 ERA, 1.20 WHIP, and 43 strikeouts. Due to his recovery from elbow surgery, the 24-year-old did not make his season debut until early August. Jobe underwhelmed upon his return, logging a 4.63 ERA and an 18.3% strikeout rate across his first five starts. However, the 24-year-old has begun to dominate in his most recent outings. Across his last 17 1/3 innings (three starts), Jobe has recorded a 3.12 ERA and an elite 35.3% strikeout rate while allowing just a 5.9% walk rate. Jobe had previously struggled to generate strikeouts in the big leagues at the same high rates he did in the minors. If he's turning the corner in that department, the hard-throwing righty carries significant upside and profiles as a must-start pitcher in his final scheduled appearance of 2026 against the Pittsburgh Pirates on Friday.

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Houston Astros starting pitcher Cristian Javier (groin) exited his start on Tuesday against the Seattle Mariners with right groin tightness, per Chandler Rome of The Athletic. The right-hander allowed a hit and two walks while striking out two across two scoreless innings before being pulled from the game. While the severity of Javier's injury is not yet clear, it could put his availability for the remainder of the season in jeopardy. Across 63 innings in 2026, Javier has recorded a 2-6 record with a 5.14 ERA, 1.46 WHIP, and 59 strikeouts. The early portion of the 29-year-old's season was wiped out by a shoulder injury, and he struggled upon his immediate return from the injury in early July. However, Javier has been much better of late, pitching to a 1.96 ERA across 18 1/3 innings in September. Fantasy managers should check back for updates on Javier ahead of his next scheduled start on Sunday against the Athletics.

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Across 427 plate appearances in 2026, Washington Nationals outfielder Dylan Crews is hitting .226/.290/.372 with 12 home runs, 43 RBI, 51 runs scored, and 11 stolen bases. While the 24-year-old's overall line may not stand out, he's made some slight improvements in the second half of the season. Crews is hitting .237 across 238 plate appearances since the All-Star break after hitting .211 across 189 plate appearances in the first half. The young outfielder has also had one of his better months in September, hitting .250 with two home runs and three stolen bases across 74 trips to the plate. Crews may never emerge as the superstar many projected him to be when he was a prospect. However, Crews may be rounding into a decent source of power, speed, and run production for deep-league managers to target on the waiver wire.

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Current Colorado Rockies infielder Connor Norby got off to a terrible start to the 2026 season while playing for the Miami Marlins, hitting .205 with four home runs across 233 plate appearances. However, the 26-year-old has turned his year around since being traded to Colorado in early August. Across 138 plate appearances with the Rockies, Norby is hitting .300/.384/.458 with three home runs, 17 RBI, 19 runs scored, and four stolen bases. There could be some small sample-size noise impacting Norby's resurgence, as his strikeout rate with Colorado remains elevated at 26.1%. However, Norby has fully taken advantage of the hitter-friendly home environment of Coors Field, hitting .303 in his home games since joining the Rockies. Norby's ability to play first, second, or third base has also helped him secure an everyday role in the Colorado lineup as a utility infielder. In his new environment, Norby profiles as a worthy waiver-wire target for fantasy managers.

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Across 79 plate appearances since making his MLB debut in late August, Minnesota Twins outfielder Walker Jenkins is hitting .214/.295/.414 with four home runs, nine RBI, 11 runs scored, and one stolen base. There's reason to believe that the 21-year-old has suffered through some poor luck at the plate, as his .224 batting average on balls in play is well below league average and significantly worse than his .340 BABIP at Triple-A this season. Jenkins has also begun to unlock his power recently, with three of his four home runs coming in his last six games played. The young center fielder is widely considered to be one of the top prospects in baseball, and he dominated Triple-A pitching by hitting .308/.407/.532 with 12 home runs, 28 RBI, 51 runs scored, and 17 stolen bases across 307 plate appearances before his promotion. In leagues where he's available on the waiver wire, Jenkins profiles as a high-upside outfielder target for fantasy managers in the final week of the 2026 season.

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Toronto Blue Jays first baseman Vladimir Guerrero Jr. (back) remains out of action for Game 1 of Wednesday's doubleheader at Camden Yards against the division-rival Baltimore Orioles, per MLB.com. Sean Keys will make another start at first base and will bat fifth against Orioles right-hander Chris Bassitt. Guerrero is considered day-to-day right now in the final week of the regular season after departing Sunday's game early against the Texas Rangers due to tightness in his lower back. It is something that the 27-year-old Canadian slugger has already dealt with this year, and it could explain why the six-time All-Star has had a very disappointing 2026 campaign. Guerrero enters play on Wednesday with a .263/.336/.359 slash line, a .695 OPS, only nine home runs, 56 RBI, 71 runs scored, and seven steals across his 529 at-bats. Toronto entered play on Wednesday four games out of the final wild-card spot in the American League and on the brink of elimination. If they lose the first game of Wednesday's doubleheader, Guerrero could be shut down for the rest of the week.

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Houston Astros shortstop Jeremy Pena (wrist) was hit on the right wrist with a 96.4 mph sinker in Tuesday's game against the Seattle Mariners and was removed in the eighth inning, according to Chandler Rome of The Athletic. Pena attempted to stay in the contest, but he was eventually replaced by Nick Allen at shortstop after going 1-for-4 at the plate with two runs scored and two strikeouts. The Astros likely sent Pena for X-rays, and we will pass along the results when we have them. Fantasy managers will want to check back later to see if the Astros' starting shortstop will be available for Wednesday's game in Seattle against the Mariners. Losing Pena for the rest of the final week of the 2026 regular season would be a huge blow, with the Astros going into Wednesday's action tied for first in the American League West with the Texas Rangers. The 29-year-old Pena has missed time this year due to various injuries, but he has been solid when healthy, slashing .275/.325/.469 with a .795 OPS, 20 home runs, 51 RBI, 77 runs scored, and 10 stolen bases in 107 games across 461 plate appearances.

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Royals' 1B Vinnie Pasquantino had five RBIs going 3-for-5 with a home run in a 14-11 loss to the White Sox on Tuesday, Sep. 22.

White Sox's SS Chase Meidroth had five RBIs going 3-for-4 with a home run in a 14-11 win over Kansas City on Tuesday, Sep. 22.

Phillies' SP Zack Wheeler recorded 11 strikeouts in 5.2 innings in a 6-4 win over the Brewers on Tuesday, Sep. 22.

Rays' SP Drew Rasmussen recorded 11 strikeouts in 6.2 innings with the win in a 6-1 win over the Yankees on Tuesday, Sep. 22.

Chicago Cubs manager Craig Counsell said that third baseman Alex Bregman (face) will not be placed on the injured list and could return to the team's lineup before the end of the regular season, per Russell Dorsey of Yahoo Sports. Bregman was struck in the face by a foul ball while standing in the on-deck circle during Chicago's game against the Cincinnati Reds on Sunday. The 32-year-old suffered multiple facial fractures, but he was able to avoid surgery and appears to be on track to return to the Cubs for the postseason. Across 693 plate appearances in 2026, Bregman is hitting .262/.352/.452 with 26 home runs, 89 RBI, 89 runs scored, and three stolen bases. He's been one of the best hitters in baseball in the second half of the season, hitting .296 with 17 home runs across 262 plate appearances since the All-Star break. With Bregman in the middle of it, the Cubs lineup profiles as arguably the best in MLB in 2026.

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