Las Vegas Raiders quarterback Kenny Pickett is set to make his first start of the season in Week 15 against the Philadelphia Eagles, per NFL Network's Ian Rapoport. Pickett entered in relief of Geno Smith (shoulder) in the Week 14 game against the Denver Broncos, and Smith is considered unlikely to start this Sunday in Philadelphia. Pickett stepped in and completed eight of 11 pass attempts for 97 yards and a touchdown after Smith left in the second half. The former first-round pick in 2022 is set to make his first start since Week 17 last season with the Eagles against the Dallas Cowboys. He completed 10 of 15 passes for 143 yards and a touchdown before leaving the game with a rib injury. He'll project as a low-end QB2 option for fantasy managers in superflex leagues in a tough road matchup if he's under center in potential inclement weather in Philly.

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Houston Texans rookie running back Woody Marks (ankle) is not practicing on Wednesday, according to Aaron Wilson of KPRC 2 Houston. Marks was listed as a non-participant in practice last Wednesday before practicing on Thursday and Friday and suiting up for the Week 14 game against the Kansas City Chiefs. The rookie fourth-rounder has operated as the Texans' clear lead back over the past five games, playing 71.1% of the snaps and averaging 20 touches per game during that span. Marks hasn't been efficient as a runner with just a 3.4 yards per carry as the workhorse, but he's earned the upper hand in the Texans' backfield ahead of veteran Nick Chubb, who also missed Wednesday's practice due to a rib injury. Marks' practice status will continue to be monitored this week ahead of Sunday's matchup against the Arizona Cardinals, but if he's active, he'll be firmly in play as an RB2 in fantasy in a strong matchup.

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Houston Texans running back Nick Chubb (rib) is not participating in Wednesday's practice session, Aaron Wilson of KPRC 2 Houston reports. Chubb could be in danger of missing the Week 15 matchup with the Arizona Cardinals after injuring his rib during the second quarter of the Texans' win over the Chiefs on Sunday night. The former Cleveland Browns running back has taken a back seat to rookie Woody Marks in recent weeks, playing just 21.4% of the snaps with 24 carries for 117 yards and a touchdown over the past five games. Marks could see an even bigger workload in Week 15 against the Cardinals if Chubb is ruled out, with Dare Ogunbowale likely to mix in more frequently as well. Fantasy managers shouldn't be planning on starting Chubb, anyway, even if he gains clearance to play in Week 15.

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Detroit Lions wide receiver Amon-Ra St. Brown (ankle) has returned to practice on Wednesday, according to Colton Pouncy of The Athletic. St. Brown didn't practice at all last week after spraining his ankle in the Thanksgiving Day loss to the Green Bay Packers in Week 13, but the 26-year-old ended up suiting up in last Thursday's win over the Dallas Cowboys. St. Brown had a gutsy performance in the 44-30 win, in which he caught six of his nine targets for 92 yards. His matchup will be a lot tougher this weekend against the Los Angeles Rams, but the Sun God should also be healthier after 10 days of rest. Even if St. Brown is at less than 100 percent on Sunday, he should be considered a must-start in all fantasy football lineups. He ranks as the WR4 in half-PPR points this year and has posted 90-plus receiving yards in five games.

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Tampa Bay Buccaneers wide receiver Jalen McMillan (neck) was limited in practice all week and is officially listed as questionable to play in Week 15 against the division-rival Atlanta Falcons on Thursday Night Football, according to the Tampa Bay Times' Rick Stroud. The Bucs' offense is getting healthy at the right time, with both McMillan and Mike Evans (collarbone) activated from Injured Reserve on Wednesday. However, they are both up in the air to be active on Thursday. The 24-year-old McMillan fractured bones in his neck and sustained ligament damage during the preseason, so he'll most likely be eased back into the offense if he's active this week. McMillan finished his rookie season strong in 2024, but he's returning to a very crowded WR room that includes Evans, Chris Godwin Jr., and rookies Emeka Egbuka and Tez Johnson. For now, McMillan is merely a stash option in deeper fantasy leagues.

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Las Vegas Raiders quarterback Geno Smith (shoulder), who is dealing with a right-shoulder injury, is unlikely to start on Sunday on the road against the Philadelphia Eagles in Week 15, sources told NFL Network's Ian Rapoport. Smith will not practice on Wednesday after injuring his right shoulder in the Week 14 loss to the Denver Broncos on Sunday. Smith's injury puts Kenny Pickett in line to start this weekend against his former team. The severity of the 35-year-old's shoulder injury is unclear. Smith has been one of the worst starting QBs in the NFL in 2025 in his first year in Vegas, completing 67% of his pass attempts for 2,648 yards, 16 touchdowns, and a league-leading 14 interceptions in 13 starts. He's also been sacked a league-high 49 times. If Pickett comes in and plays well, it wouldn't be a surprise if Smith is benched for the final three games.

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Tampa Bay Buccaneers wide receiver Mike Evans (collarbone) was limited in practice all week and is officially questionable to play on Thursday night against the division-rival Atlanta Falcons in Week 15, according to Rick Stroud of the Tampa Bay Times. Evans was activated from Injured Reserve on Wednesday, though, and head coach Todd Bowles said that the 32-year-old future Hall of Famer has done everything he's needed to do to be active this week for the first time since breaking his collarbone in Week 7. The veteran pass-catcher has yet to take contact in practice, though, so he's iffy to play on Thursday night. But the Bucs are desperate for a win as they seek to stay atop the NFC South division. Evans needs to be rostered in all fantasy leagues, but he'll be a pretty shaky starting option if he's active while being at risk of limited snaps in his first game back.

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New York Giants interim head coach Mike Kafka said that running back Tyrone Tracy Jr. (hip) is "good to go" for the Week 15 game this Sunday against the division-rival Washington Commanders after suffering a hip injury in the Monday night loss to the New England Patriots before the Week 14 bye, per Dan Salomone of Giants.com. Tracy suffered a bruised hip in Week 13 and had to be carted off the field, but he's back at practice on Wednesday and should be active in D.C. The 26-year-old's presence this weekend in New York's backfield will be bad news for fantasy managers who picked up Singletary, hoping that he'd operate as the Giants' clear lead back. Tracy and Singletary could end up sharing touches down the middle on Sunday, making them both RB3/flex options in fantasy lineups. Tracy has seen double-digit carries in each of the last four games, but he has just one touchdown on the year (back on Oct. 19).

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Dallas Cowboys head coach Brian Schottenheimer said on Wednesday that wide receiver CeeDee Lamb (concussion) is "progressing nicely" and has "one or two" more things left to clear the league's concussion protocol, according to Tommy Yarrish of DallasCowboys.com. Lamb will probably be listed as limited on the team's injury report on Wednesday, but he was seen going through drills despite suffering a concussion in last Thursday night's loss to the Detroit Lions. Until the 26-year-old is officially cleared from concussion protocol, he'll be considered questionable to play on Sunday Night Football against the Minnesota Vikings. However, as of now, it's looking like he's on the right side of questionable. Ryan Flournoy went off for nine catches, 115 yards, and a touchdown on 13 targets in Week 14 with Lamb injured, making him a popular speculative waiver-wire pickup if Lamb doesn't gain clearance to play this weekend. If Lamb is active, he'll be a must-start in all fantasy lineups in Week 15.

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Washington Commanders head coach Dan Quinn said that the team is not talking about shutting down quarterback Jayden Daniels (elbow) for the year, according to Tom Schad of Post Sports. Daniels has been ruled out for Sunday's game against the New York Giants after aggravating his left elbow during last week's loss to the Minnesota Vikings in his first game since dislocating his elbow in Week 9. The second-year quarterback is expected to play again this season, as the injury is not considered to be a long-term issue, but the possibility that Daniels doesn't return this season appears more likely now. The reigning Offensive Rookie of the Year's sophomore season has been overshadowed by injury, as he also missed two games to a knee injury and one game to a hamstring injury before his elbow issue. Marcus Mariota is set to make his seventh start of the year in Week 15 versus the Giants at MetLife Stadium.

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Green Bay Packers running back Josh Jacobs (knee) is not practicing on Wednesday, Bill Huber of Sports Illustrated reports. Jacobs was the lone Packers player not participating in Wednesday's practice session. The veteran was seen riding a bike and doing rehab work off to the side as practice began. It's not a great sign for the 28-year-old to open the week, but the team is likely just giving him a rest day. The 28-year-old missed Green Bay's Week 12 matchup against the Minnesota Vikings after injuring his knee in Week 11 against the New York Giants, but he returned for the Packers' past two games and handled his normal workload. If Jacobs winds up missing the Week 15 game versus the Denver Broncos, Emanuel Wilson would be in line to make another spot start. Jacobs is a must-start in fantasy lineups when active.

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Baltimore Ravens quarterback Lamar Jackson (ankle) is not practicing on Wednesday, per ESPN's Jamison Hensley. Jackson has now missed at least one day of practice for the fifth straight week as he has been limited by ankle, knee, and toe ailments over the last few weeks after missing multiple games with a hamstring injury earlier in the year. The star quarterback hasn't quite looked like himself since returning in Week 9, completing 58.7% of his passes with six touchdowns to four interceptions while totaling 38 rushing attempts for 141 yards and one touchdown, which came this past week against the Pittsburgh Steelers. Jackson will likely return to practice in some capacity on Thursday and Friday and be good to go for the Week 15 divisional matchup against the Cincinnati Bengals.

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Arizona Cardinals wide receiver Marvin Harrison Jr. (heel) is not participating in Wednesday's practice session, per Darren Urban of AZCardinals.com. Harrison returned in Week 13 against the Tampa Bay Buccaneers after missing Weeks 11 and 12 due to an appendectomy, but then he missed the Week 14 game against the Los Angeles Rams after being listed as a DNP every day of practice last week with a heel injury. The second-year wideout is in danger of missing his fourth game in five weeks. It's been a frustrating season for Harrison, as he's struggled to stay healthy and hasn't taken a big step forward when he's been on the field, totaling 40 receptions for 594 yards and four touchdowns on 69 targets in 10 games. If Harrison is forced to miss the Week 15 game against the Houston Texans, Michael Wilson would be in line to see another heavy target share.

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Atlanta Falcons tight end Kyle Pitts Sr. (knee) tied a season-high on Sunday with 10 targets and eclipsed his season-high yardage total -- which was set in Week 13 -- with 90 yards receiving on six catches. He did not find the end zone, as he's still sitting with just one touchdown on the season, but the 25-year-old has been plenty useful on volume alone, especially in PPR leagues. With Drake London (knee) missing the last three games (and also Week 8), the 6-foot-6 tight end has become Kirk Cousins' favorite pass-catcher, averaging eight targets, six receptions, and 64 yards receiving per contest in the four games with Cousins under center this season. Pitts popped up on the injury report earlier in the week with a knee injury and was a limited participant up to and including Wednesday's practice, resulting in a questionable designation for Thursday's matchup on the road against the Buccaneers. London, however, has been ruled out for TNF, so Pitts could be in line to maintain his temporary status as the team's No. 1 receiver again in Week 15 so long as he's active. Tampa Bay is middle of the pack in terms of fantasy points allowed to opposing tight ends, but the fifth-year pro shapes up as a mid-range TE1 for Thursday, so fantasy managers will want to double-check his status before kickoff.

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Indianapolis Colts quarterback Anthony Richardson Sr. (eye) was present at Wednesday's practice for the first time in weeks, James Boyd of The Athletic reports. Head coach Shane Steichen said on Monday that Richardson wouldn't be activated off Injured Reserve this week, but he also hasn't been ruled out for the season. It's a positive development for the 2023 fourth overall pick, who suffered an orbital fracture in pre-game warmups before the Colts' Week 6 matchup against the Arizona Cardinals. With Daniel Jones out for the season with a torn Achilles and rookie Riley Leonard's status up in the air due to a knee injury, the Colts signed 44-year-old Philip Rivers on Tuesday, and he could start as soon as Sunday against the Seattle Seahawks. Richardson is still in play to return this season, though his timeline is uncertain. His status will be worth monitoring now that he is seemingly getting closer to making a return.

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New York Jets quarterback Justin Fields (knee) is not practicing on Wednesday, per ESPN's Rich Cimini. Fields came down with a sore knee last week and was held out of the Week 14 loss to the Miami Dolphins on Sunday. The 26-year-old, who has lost the starting QB job, is in danger of missing a second straight game this weekend against the Jacksonville Jaguars unless he can get back on the field in the next two days. Tyrod Taylor (groin) isn't practicing on Monday either, after getting injured in Sunday's loss to Miami. There's a scenario where Fields could make the start this weekend if he's able to get past his knee injury and Taylor is ruled out. If both Taylor and Fields aren't cleared to play in Week 15, undrafted rookie Brady Cook would make his first NFL start. That would be bad news for all of New York's offensive skill players.

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Atlanta Falcons wide receiver Drake London (knee) has been ruled out for the Thursday night game against the division-rival Tampa Bay Buccaneers in Week 15, according to Marc Raimondi of ESPN. The writing was on the wall for London to miss a fourth straight game after he missed practice on both Monday and Tuesday. The 24-year-old hasn't practiced or played since spraining his PCL back in Week 11. Fantasy managers who stay alive in the playoffs will be hoping that London can return to practice next week and play in Week 16 versus the Arizona Cardinals. With London sidelined again this week, Darnell Mooney will once again be Atlanta's WR1, although he'll be a volatile WR4/flex. Mooney had 74 yards and a touchdown in the first game without London, but in the last two weeks, he's caught only three passes for 31 yards. Tight end Kyle Pitts Sr. has benefited the most in the last three weeks with London out.

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New York Giants running back Tyrone Tracy Jr. (hip) is at practice on Wednesday, according to Jordan Raanan of ESPN. Tracy suffered a bruised hip in the Monday night loss to the New England Patriots in Week 13, but he had the Week 14 bye to rest up and is now back at practice as the Giants begin preparations for a Week 15 divisional clash this Sunday against the Washington Commanders. The 26-year-old's injury didn't look good at the time, and he had to be carted to the locker room. He'll probably end up limited on Wednesday, but his presence at practice is a good sign for his availability this weekend. Devin Singletary had 15 touches in Week 13 for 102 scrimmage yards and a touchdown, which has made him a popular waiver-wire pickup going into the fantasy playoffs. Singletary's upside in Week 15 will take a hit, though, if Tracy is able to return to New York's backfield.

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New York Jets quarterback Tyrod Taylor (groin) is not taking part in practice on Wednesday, according to Rich Cimini of ESPN. Justin Fields (knee) isn't practicing either, so undrafted rookie QB Brady Cook will take the first-team reps under center. Taylor made the start in Week 14 against the Miami Dolphins, but injured his groin early and was replaced by Cook. The 36-year-old veteran went just 1-for-4 passing for six yards and an interception on Sunday. Taylor has two more days to get back on the practice field, but he should be considered questionable to play in Week 15 against the first-place Jacksonville Jaguars on Sunday. He has boosted New York's passing game slightly since taking over the starting gig from Fields, but he doesn't offer very much upside at all in fantasy football. Taylor has completed 59.7% of his passes for 779 yards, five TDs, and five picks in his six games (four starts) in 2025.

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The New York Jets have yet to open the 21-day practice window for wide receiver Garrett Wilson (knee), according to ESPN's Rich Cimini. Head coach Aaron Glenn reiterated that the team still has to consult with doctors on Wilson's status. Wilson remains on Injured Reserve after aggravating a knee injury back in Week 10. At this point, with only four games remaining in the 2025 season, it's fair to wonder if the 25-year-old pass-catcher will be allowed to come back with the Jets out of playoff contention. With Wilson almost certain to be ruled out for Week 15 against the Jacksonville Jaguars, receivers John Metchie III and Adonai Mitchell will continue to operate as the top two receivers, but they might be taking passes from undrafted rookie quarterback Brady Cook this week with both Tyrod Taylor (groin) and Justin Fields (knee) nursing injuries.

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