Guest of the League
Lineup Changes
Bucs - Scott
| Benched | WR | Tyreek Hill MIA | Owner | Sun Nov 10 9:25am ET |
| Started | WR | Josh Palmer LAC | Owner | Sun Nov 10 9:25am ET |
| Started | K | Jake Bates DET | Owner | Thu Nov 7 5:40am ET |
Canes - Gordon Drake
| Benched | RB | Tyler Allgeier ATL | Owner | Sun Nov 10 9:57am ET |
| Started | RB | Christian McCaffrey SF | Owner | Sun Nov 10 9:57am ET |
| Benched | WR | Parker Washington JAX | Owner | Thu Nov 7 8:23am ET |
| Started | WR | Jameson Williams DET | Owner | Thu Nov 7 8:23am ET |
| Benched | RB | Tank Bigsby JAX | Owner | Wed Nov 6 11:05pm ET |
| Benched | WR | Gabriel Davis JAX | Owner | Wed Nov 6 11:05pm ET |
| Started | RB | Tyler Allgeier ATL | Owner | Wed Nov 6 11:05pm ET |
| Started | WR | George Pickens PIT | Owner | Wed Nov 6 11:05pm ET |
Chargers - Alex Sahrane
| Started | WR | Nico Collins HOU | Owner | Sun Nov 10 11:43am ET |
| Started | WR | Ricky Pearsall SF | Owner | Thu Nov 7 7:59pm ET |
| Benched | K | Younghoe Koo ATL | Owner | Thu Nov 7 8:49am ET |
| Started | K | Chris Boswell PIT | Owner | Thu Nov 7 8:49am ET |
| Started | D/ST | Philadelphia Eagles PHI | Owner | Thu Nov 7 8:49am ET |
Colts - Eddie Giles
| Benched | RB | Nick Chubb CLE | Owner | Tue Nov 5 11:55am ET |
| Started | WR | Josh Downs IND | Owner | Tue Nov 5 11:55am ET |
Cowboys - Charlie Giles
| Started | RB | Jaylen Warren PIT | Owner | Fri Nov 8 6:01pm ET |
| Benched | RB | Brian Robinson Jr. WAS | Owner | Fri Nov 8 6:01pm ET |
| Started | RB | Brian Robinson Jr. WAS | Owner | Tue Nov 5 7:15am ET |
| Benched | RB | Justice Hill BAL | Owner | Tue Nov 5 7:15am ET |
| Started | TE | George Kittle SF | Owner | Tue Nov 5 7:14am ET |
| Started | WR | Deebo Samuel SF | Owner | Tue Nov 5 7:14am ET |
| Started | QB | Aaron Rodgers NYJ | Owner | Tue Nov 5 7:14am ET |
| Benched | WR | Cedric Tillman CLE | Owner | Tue Nov 5 7:14am ET |
| Benched | WR | Jayden Reed GB | Owner | Tue Nov 5 7:14am ET |
| Benched | QB | Caleb Williams CHI | Owner | Tue Nov 5 7:14am ET |
Dolphins - Phil Healy
| Started | WR | Noah Brown WAS | Owner | Thu Nov 7 1:08am ET |
| Benched | WR | Diontae Johnson BAL | Owner | Thu Nov 7 1:08am ET |
| Started | WR | Diontae Johnson BAL | Owner | Wed Nov 6 10:24pm ET |
| Benched | WR | Romeo Doubs GB | Owner | Wed Nov 6 10:24pm ET |
| Started | RB | Saquon Barkley PHI | Owner | Wed Nov 6 10:24pm ET |
| Benched | RB | Najee Harris PIT | Owner | Wed Nov 6 10:24pm ET |
| Started | RB | Kareem Hunt KC | Owner | Wed Nov 6 10:23pm ET |
| Benched | RB | Saquon Barkley PHI | Owner | Wed Nov 6 10:23pm ET |
| Started | RB | Najee Harris PIT | Owner | Wed Nov 6 10:23pm ET |
| Benched | RB | Kareem Hunt KC | Owner | Wed Nov 6 10:23pm ET |
| Started | TE | Cole Kmet CHI | Owner | Wed Nov 6 10:22pm ET |
| Benched | TE | Brock Bowers LV | Owner | Wed Nov 6 10:22pm ET |
| Started | WR | Calvin Ridley TEN | Owner | Wed Nov 6 10:22pm ET |
| Benched | WR | Chris Olave NO | Owner | Wed Nov 6 10:22pm ET |
Eagles - Keith Krieger
| Started | K | Younghoe Koo ATL | Owner | Sun Nov 10 7:36am ET |
| Started | K | Blake Grupe NO | Owner | Thu Nov 7 4:50pm ET |
| Benched | WR | Wan'Dale Robinson NYG | Owner | Wed Nov 6 8:40pm ET |
| Started | WR | Puka Nacua LAR | Owner | Wed Nov 6 8:40pm ET |
| Benched | WR | Puka Nacua LAR | Owner | Tue Nov 5 1:40pm ET |
| Started | WR | Wan'Dale Robinson NYG | Owner | Tue Nov 5 1:40pm ET |
| Benched | WR | Jakobi Meyers LV | Owner | Tue Nov 5 1:39pm ET |
| Started | WR | Rome Odunze CHI | Owner | Tue Nov 5 1:39pm ET |
Jags - Gary Byers
| Benched | WR | Keon Coleman BUF | Owner | Fri Nov 8 2:50pm ET |
| Started | WR | Michael Wilson ARI | Owner | Fri Nov 8 2:50pm ET |
| Benched | WR | Michael Pittman Jr. IND | Owner | Fri Nov 8 2:46pm ET |
| Started | RB | Dare Ogunbowale HOU | Owner | Fri Nov 8 2:46pm ET |
| Started | K | Evan McPherson CIN | Owner | Thu Nov 7 12:04pm ET |
| Benched | QB | Sam Darnold MIN | Owner | Tue Nov 5 2:00pm ET |
| Started | QB | Kirk Cousins ATL | Owner | Tue Nov 5 2:00pm ET |
| Benched | RB | Kenneth Walker III SEA | Owner | Tue Nov 5 12:00pm ET |
| Started | RB | Roschon Johnson CHI | Owner | Tue Nov 5 12:00pm ET |
Jets - Chris Roon
| Benched | WR | Amari Cooper BUF | Owner | Sun Nov 10 11:16am ET |
| Started | WR | Jalen Nailor MIN | Owner | Sun Nov 10 11:16am ET |
| Benched | WR | Tyler Lockett SEA | Owner | Wed Nov 6 10:06pm ET |
| Started | WR | Xavier Legette CAR | Owner | Wed Nov 6 10:06pm ET |
Raiders - Rob McGrath
| Started | TE | Jonnu Smith MIA | Owner | Thu Nov 7 11:24am ET |
The Bears - Memo
| Benched | RB | Braelon Allen NYJ | Owner | Fri Nov 8 8:41am ET |
| Started | WR | Alec Pierce IND | Owner | Fri Nov 8 8:41am ET |
| Benched | RB | Josh Jacobs GB | Owner | Fri Nov 8 8:39am ET |
| Started | RB | Devin Singletary NYG | Owner | Fri Nov 8 8:39am ET |
| Started | D/ST | San Francisco 49ers SF | Owner | Fri Nov 8 8:39am ET |
| Benched | QB | Joe Flacco IND | Owner | Wed Nov 6 10:32am ET |
| Benched | TE | David Njoku CLE | Owner | Wed Nov 6 10:32am ET |
| Started | QB | C.J. Stroud HOU | Owner | Wed Nov 6 10:32am ET |
| Started | TE | Hunter Henry NE | Owner | Wed Nov 6 10:32am ET |
Vikings - James Connell
| Benched | WR | Jaxon Smith-Njigba SEA | Owner | Tue Nov 5 5:16pm ET |
| Started | WR | Courtland Sutton DEN | Owner | Tue Nov 5 5:16pm ET |
