Buffalo Bills running back Latavius Murray seems to have usurped Damien Harris as the team's No. 2 tailback behind James Cook through the opening two weeks of play. The 33-year-old has surprisingly out-snapped Harris in consecutive outings, and he was even seen participating in two-minute drills in Week 2's romping of the Las Vegas Raiders. Murray has also unexpectedly led the backfield in red-zone touches (five), putting a frustrating damper on Cook's ceiling potential in the early goings. As it appears, Buffalo exhibits more trust in the power backs, Murray and Harris, on the goal line than Cook at this interval of the year, so Murray's usage is worth monitoring moving ahead. As far as Week 3 against the Washington Commanders goes, the veteran journeyman is a last-gasp RB4 at best with extreme touchdown dependency.

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Baltimore Ravens wide receiver Odell Beckham Jr. (ankle) has officially been ruled out for the Week 3 matchup against the Colts. Originally, the team believed that this injury wasn't going to cause the veteran wideout to miss any time. He was unable to practice at all this week which led up to ruling him out altogether. Beckham has yet to make his presence felt with this receiving corps as he only has five catches for 66 yards through two games. While he's on the sidelines, Nelson Agholor, who posted a solid game in Week 2, will see more opportunities. Agholor is still just a deeper league, low-end flex option as Mark Andrews and Zay Flowers will likely see their value increase even more.

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Green Bay Packers wide receiver Christian Watson (hamstring) has drawn a questionable tag for the Week 3 game on Sunday against the New Orleans Saints. Watson has been held out of the first two games of the year, but he practiced on Wednesday and Friday this week while being rested on Thursday. The 24-year-old second-year pass-catcher could end up being a game-time decision, so fantasy managers will need to check back on Sunday morning before deciding whether to plug him into their lineups. Watson is expected to be quarterback Jordan Love's top target this year when healthy, but he'll be a risky flex play for fantasy managers if he makes his debut on Sunday because of the fact that he could be eased into the offense with a hamstring injury that has been bothering him since late in training camp.

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Buffalo Bills tight end Dalton Kincaid saw his role expand just a bit in Week 2's trouncing of the Las Vegas Raiders. After catching five out of six balls for 43 yards last Sunday, the 23-year-old is now up to nine receptions on 10 targets for 69 yards over the first two games of his career. Dawson Knox, on the other hand, has generated nine targets for a less impressive six receptions and 35 yards, but he did manage a short touchdown catch in his last time out. On tap for the duo in Week 3 are the Washington Commanders, who have restricted Zach Ertz and Adam Trautman to 21 scoreless yards on 11 combined targets across two games. Kincaid loses a bit of appeal as a fringe TE1/2 after Knox returned to a full practice on Friday, but the first-round rookie should be stashed wherever possible. It will be hard to grade Kincaid as a confident fantasy starter until he pulls away in the even opportunity split with Knox.

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Baltimore Ravens running back Justice Hill (toe) didn't practice all week and has been officially ruled out for Week 3 against the Indianapolis Colts. Hill picked up turf toe in the Week 2 win over the Cincinnati Bengals in his first game with a bigger role due to J.K. Dobbins' season-ending Achilles injury. Turf-toe injuries can be pretty painful, so there's no guarantee Hill will be ready to roll for a Week 4 contest on the road against the Cleveland Browns next Sunday, Oct. 1. With Hill out, Gus Edwards should handle an even heavier workload and now has clear RB2 upside in a nice matchup against Indy. Melvin Gordon III will serve as Edwards' clear backup. The Ravens also signed Kenyan Drake this week for more RB insurance.

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Minnesota Vikings head coach Kevin O'Connell said it's too soon for running back Cam Akers to make his team debut in Week 3 against the Los Angeles Chargers this Sunday after the team just acquired him in a trade from the Los Angeles Rams earlier this week. Akers will likely be inactive with an eye toward playing in Week 3 against the Carolina Panthers. Akers' fantasy value could be salvaged this year as a complement to Alexander Mattison after wearing out his welcome with the Rams, but fantasy managers must remember that the 24-year-old now has to learn a completely new offense in short order. Mattison will continue to operate as Minnesota's clear lead back this Sunday, with Ty Chandler serving as a change-of-pace option in the backfield.

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Green Bay Packers running back Aaron Jones (hamstring) is being listed as questionable to play in Week 3 on Sunday at home against the visiting New Orleans Saints. Jones didn't practice all of last week and was inactive in the Week 2 loss to the Atlanta Falcons. He missed practice on Wednesday but was able to return to a limited session on Thursday, which gives him a chance to play this weekend. The 28-year-old could be a true game-time decision, so fantasy managers will need to check back Sunday morning before finalizing their weekly lineups. Jones is trending as a shaky RB3/flex in Week 3 because of his hammy injury, but if he's active, it's hard to recommend sitting him after he went for 41 yards and a touchdown on nine carries on the ground while adding two catches for 86 yards and another score through the air in the season opener. If he sits again, AJ Dillon will get another crack as the lead back.

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Miami Dolphins kicker Jason Sanders is on the lower end of the top-12 kicking options heading into Week 3 against the Denver Broncos. He posted a great game in Week 1 during the shootout against the Chargers but only made one of his three field goal attempts in Week 2 against the Patriots. Sanders seems to be more relevant in streaming situations when the Dolphins are in for a high-scoring affair. The Broncos don't have a great defense but kickers have only averaged seven fantasy points per game against them so far. There are better options out there, but Sanders isn't the worst play this week.

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Minnesota Vikings left tackle Christian Darrisaw (ankle) returned to practice this week and was removed from the final injury report on Friday, meaning he will return to play against the Los Angeles Chargers in Week 3 on Sunday. Darrisaw suffered an ankle injury in the season-opening loss to the Tampa Bay Buccaneers and was forced to sit out in the loss to the Philadelphia Eagles on a short week last Thursday night. The 24-year-old wasn't officially inactive last Thursday, but the Vikings chose not to put him in the game, even after fill-in left tackle Olisaemeka Udoh was injured in the game. Darrisaw's return will be great news for quarterback Kirk Cousins and the Vikings offense as they seek their first win of 2023.

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Running back Damien Harris managed to find the end zone amid Week 2's smackdown of the Las Vegas Raiders for the first touchdown of his Buffalo Bills career. The 26-year-old finds himself in an intimidating matchup on deck against the Washington Commanders' stud nose-tackle combination of Jonathan Allen and Daron Payne. Harris has played behind Latavius Murray for scraps behind lead back James Cook in the opening two weeks, so fantasy managers would really be grasping at straws by inserting Harris into Week 3 lineups. Murray has siphoned five of Buffalo's nine red-zone touches among the three RBs. The power back, Harris, is at least a better bet to hit paydirt than Cook after out-touching him in the red zone 4-0 to this point. Harris probably needs Sunday's meeting to get out of hand in favor of Buffalo to return value as a TD-or-bust RB4/FLEX.

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The Miami Dolphins defense/special teams has seen extreme lows and moderate highs after the first two weeks of the season. They have the talent to force some turnovers and wrack up the sacks, but they've also shown some massive holes that offenses can exploit. On the brighter side, the Broncos offense is very inconsistent and has one of the lowest-ranked receiving and backfield groups in the league according to PFF. If Jaelan Phillips plays in this contest, it will improve the entire unit and they become a bit better of a play. For managers desperate for some defensive output, the Dolphins are a gamble, but have some solid upside.

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Las Vegas Raiders head coach Josh McDaniels said that wide receiver Jakobi Meyers (concussion) is good to go to play in the Week 3 game against the Pittsburgh Steelers in the team's home opener on Sunday Night Football. Meyers was able to clear the league's concussion protocol and returned to a full practice on Thursday, setting the stage for him to return after missing the Week 2 loss to the Buffalo Bills. The 26-year-old made a nice impression in his debut for the Raiders in the season opener, catching nine of his 10 targets for 81 yards and two touchdowns before suffering a concussion. He'll return to the No. 2 role behind Davante Adams against Pittsburgh and is back on the fantasy radar as a WR4/flex option for managers this weekend.

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Buffalo Bills tight end Dawson Knox (back) was upgraded to a full practice on Friday and was removed from the final injury report for Week 3 against the Washington Commanders on Sunday. Knox missed practices on both Wednesday and Thursday, so it was looking like he'd at least be questionable to play this weekend. It's bad news for those hoping for a big game from rookie Dalton Kincaid in the potential absence of Knox, but it looks like Knox will be active after all. Through two games, Knox has six catches on his nine targets for 35 yards and a touchdown. He has played more offensive snaps than Kincaid to this point, but Kincaid has outproduced him (minus the TD) with nine catches for 69 yards early in the year.

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Buffalo Bills running back James Cook excited fantasy managers with a huge 159-yard showing in Week 2's dismantling of the Las Vegas Raiders. The 23-year-old next challenges the Washington Commanders, who have held James Conner and Javonte Williams to scoreless 14/62 and 12/44 rushing lines respectively in the opening two games. Washington's defense has proven to be slightly more vulnerable in the backend with their ravenous defensive line, if anything, so Cook will likely need to break away for some explosive runs on the outside to penetrate this unit. Buffalo has constantly utilized him on counter plays, so expect that usage to persist in an effort to get the dynamic Cook to the second level of the field. Due to zero red-zone touches on the young season, however, the 2022 second-rounder is stuck as a high-floor RB2 in Week 3 and until further notice.

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Indianapolis Colts rookie quarterback Anthony Richardson (concussion) will miss the Week 3 game against the Baltimore Ravens this Sunday as he remains in the league's concussion protocol. However, a source said that Richardson is optimistic about playing in Week 4 against the Los Angeles Rams, assuming he passes through the protocols next week. The Colts and Richardson have been cautious this week in their discussions about his return. Veteran Gardner Minshew entered for the concussed Richardson in last week's win over the Houston Texans and threw for 171 yards on 19-for-23 passing with a touchdown and no interceptions. Minshew will make the start this weekend for the first time since Week 17 last season while playing for the Philadelphia Eagles.

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Wide receiver Gabe Davis asserted himself as a legitimate No. 2 option alongside Stefon Diggs by leading the Buffalo Bills with 92 receiving yards and a touchdown in Week 2's vanquishing of the Las Vegas Raiders. The 24-year-old is likely to square off frequently with top Washington defensive back Kendall Fuller, who helped lock down the Arizona Cardinals in the season opener, but gave way a bit for a 3/69/1 receiving line against him in Week 2 versus the Denver Broncos. There's not much else to be said about Davis on a weekly basis; his every-down role in a pass-heavy offense keeps him in the WR3 conversation. But the deep threat is of the boom-or-bust variety in Week 3, and Davis may not find breathing room as easily against the Commanders as it came last time out versus the inferior Raiders secondary.

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Philadelphia Eagles running back Boston Scott (head) has cleared the league's concussion protocol and returned to practice on Friday after being limited on Thursday. Kenneth Gainwell (ribs) is also practicing for the second straight day this week after he missed last Thursday's win over the Minnesota Vikings. Scott suffered a concussion early in the Week 2 game but has benefitted from the extra time off and should be ready to go on Monday night against the Tampa Bay Buccaneers unless he suffers a setback on Saturday. With Gainwell looking likely to play as well this week, the 28-year-old Scott will most likely have a limited role in Philly's backfield and won't be a viable flex play in fantasy. In the season opener when the backfield was fully healthy, he had just one carry for three yards and caught one pass for seven yards.

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Washington Commanders tight end Logan Thomas (concussion) did not clear the league's concussion protocol and will not play in Week 3 against the Buffalo Bills on Sunday. The oft-injured Thomas made it just two games before picking up another injury, and he'll miss his first game of the 2023 campaign. The 32-year-old will need to clear the concussion protocol next week in order to have a shot at returning in a Week 4 contest on the road in Philadelphia against the Eagles. With Thomas out this Sunday against Buffalo, expect both John Bates and Cole Turner to see expanded roles in the passing game, but neither of them should warrant serious consideration as streaming options at the tight end position.

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Buffalo Bills wide receiver Stefon Diggs played second fiddle to teammate Gabe Davis' 92 yards and a score with 66 scoreless yards in Week 2's triumph over the Las Vegas Raiders. The 29-year-old next does battle with the Washington Commanders secondary, who just saw rookie Marvin Mims Jr. dust them up for 113 yards and a touchdown on two targets last Sunday. Diggs likely draws the more favorable matchup between himself and Davis in Week 3, as he looks to pick on first-round rookie Emmanuel Forbes Jr. in this one, while Davis perhaps deals more regularly with top Commanders corner Kendall Fuller. Having caught 17-of-20 targets for 168 yards to start the campaign after a rocky offseason, Diggs has relieved any fear that his harmony with quarterback Josh Allen would be compromised in 2023. The three-time Pro Bowler rates as a high-floor WR1 in this one with four red-zone targets thus far.

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Washington Commanders wide receiver Curtis Samuel (illness) missed practice on Friday due to an illness and is now questionable to play in Week 3 on Sunday at home against the visiting Buffalo Bills. We would be surprised if Samuel doesn't end up suiting up this weekend, but those that were planning on starting him in a flex spot against the Bills in deeper leagues will need to pay close attention to his final status on Sunday morning. Samuel has a low fantasy ceiling and floor as the No. 3 receiver in Washington, and he has eight catches on eight targets for 73 yards in the first two weeks of the season. If the veteran is out or limited in Week 3, Dyami Brown could have a decent role, especially with tight end Logan Thomas (concussion) already being ruled out.

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