New England Patriots running back Antonio Gibson (knee), who was quickly ruled out in the Sunday night win over the Buffalo Bills in Week 5, suffered a torn ACL and will miss the rest of the season, sources told NFL Network's Ian Rapoport after Gibson had an MRI exam on Monday. It's a hit to New England's backfield the rest of the way. The 27-year-old will finish the 2025 campaign with 25 rushing attempts for 106 yards and one touchdown. He added two catches for six yards on three targets through the air. Gibson wasn't really a roster candidate in 12-team fantasy leagues, but he can now safely be dropped in deeper single-year formats. Terrell Jennings will likely be elevated from the practice squad to serve as the RB3 behind Rhamondre Stevenson and rookie TreVeyon Henderson. Gibson's injury gives Henderson a clearer path to an elevated backfield workload.

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Los Angeles Chargers running backs Kimani Vidal and Hassan Haskins are now in line for the bulk of the backfield load with rookie Omarion Hampton (ankle) going on Injured Reserve on Monday, according to Eric Smith of Chargers.com. Najee Harris (Achilles) is also out for the season. Vidal had 18 rushing yards on four carries in the Week 5 loss to the Washington Commanders, with Haskins carrying the ball five times for 13 yards. The Chargers will most likely call up Amar Johnson to serve as the RB3 for at least the next four games with Hampton sidelined. Both Vidal and Haskins played 14 offensive snaps on Sunday versus Washington, but it's unclear exactly how the workload will be divvied up between Vidal and Haskins moving forward. Still, both RBs are worth attention on the waiver wire this week, with an increase in volume coming for the next four games.

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San Francisco 49ers wide receiver Ricky Pearsall (knee) wasn't spotted at Monday's practice, according to Cam Inman of the Bay Area News Group. Although the 49ers didn't hold an official practice on Monday, it's not a great sign that Pearsall isn't on the field after he was inactive for last Thursday night's win over the Los Angeles Rams due to a minor PCL injury that he suffered in Week 4. Both Pearsall and Jauan Jennings (ankle, ribs) did not play last Thursday, allowing Kendrick Bourne to go off for 10 catches and over 100 yards. Jennings was on the field on Monday, though, signaling that Jennings might be closer than Pearsall in terms of being available in Week 6 to face the Tampa Bay Buccaneers. If the 25-year-old Pearsall doesn't return to the team's first practice on Wednesday, he'll be on track to miss a second straight game.

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The bulk of the Los Angeles Chargers' backfield will now likely fall to running backs Hassan Haskins and Kimani Vidal, writes Eric Smith of Chargers.com. The Chargers placed rookie RB Omarion Hampton (ankle) on Injured Reserve on Monday after they already lost veteran Najee Harris (Achilles) for the season. Haskins had five carries for 13 yards in the Week 5 loss to the Washington Commanders on Sunday, while Vidal had 18 rushing yards on four rushing attempts. Haskins and Vidal logged 14 offensive snaps apiece on Sunday, but it's unclear exactly how the division of labor will be distributed between the two over the next four games with Hampton out. It could be a split down the middle of backfield touches, but either way, both Haskins and Vidal will be prime waiver-wire targets for fantasy managers who need help at the position. Amar Johnson should be brought up from the practice squad to serve as the RB3.

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Los Angeles Chargers rookie first-round running back Omarion Hampton (ankle) was placed on Injured Reserve on Monday after suffering an ankle injury in the Week 5 loss to the Washington Commanders. However, Ian Rapoport of NFL Network reports that Hampton has a "good chance" to miss the minimum of four games. If Hampton only needs four games to rest up, he could return on Nov. 9 against the Pittsburgh Steelers in Week 10. Najee Harris (Achilles) is already out for the entire season after tearing his Achilles, so now the Chargers are down to Hassan Haskins and Kimani Vidal in the backfield as they head into a Week 6 matchup against the Miami Dolphins on the road this Sunday. It's a tough break for the Chargers and for Hampton's fantasy managers, but he needs to remain stashed and should return to his RB1 role when he's activated from IR. In the meantime, Haskins and Vidal are likely to form a timeshare, with the Bolts also probably relying on quarterback Justin Herbert's arm and legs more.

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Minnesota Vikings head coach Kevin O'Connell said quarterback Carson Wentz (shoulder) is undergoing further evaluation on the shoulder injury he suffered during the team's Week 5 win over the Cleveland Browns. Wentz was able to finish the game, but it sounds like he "came in pretty sore," per Alec Lewis of The Athletic. The Vikings have a bye in Week 6, so Wentz will have some time to heal before the team's next game. Minnesota quarterback J.J. McCarthy (ankle) could also be back from the ankle injury that has sidelined him for the last three games by that time as well. It's not clear who the Vikings will turn to under center if both quarterbacks are available. If neither Wentz nor McCarthy is healthy in Week 7, rookie quarterback Max Brosmer could be the next man up in Minnesota.

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Detroit Lions rookie wide receiver Isaac TeSlaa had one target in Week 5 against the Cincinnati Bengals, but he made it count by turning it into a 12-yard touchdown reception. TeSlaa has made the most of his low-usage role so far this season, as he has three catches for 54 yards and two touchdowns on five targets through the first five games of his career. Perhaps most importantly for his fantasy outlook, Lions wide receiver Kalif Raymond (neck) left early in Week 5 with a neck injury and did not return. TeSlaa has been firmly behind Raymond in snap share so far this season, so an injury to Raymond could open the door for TeSlaa to take over as Detroit's WR3 alongside Amon-Ra St. Brown and Jameson Williams. It's too soon to count on TeSlaa for fantasy production, even if Raymond does miss time. Still, TeSlaa is a player to monitor in deep leagues, as he's flashed upside and could now be in line for an increased role.

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Jacksonville Jaguars tight end Brenton Strange (hip) is questionable to return to his team's Week 5 matchup against the Kansas City Chiefs due to a hip injury. Strange recorded one catch for 22 yards on one target before getting injured. If he is unable to return, Jaguars tight ends Johnny Mundt and Hunter Long would likely handle the majority of the snaps the rest of the way in Week 5.

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Buffalo Bills head coach Sean McDermott said wide receiver Keon Coleman did not play in the team's first offensive series against the New England Patriots in Week 5 for disciplinary reasons. Per The Athletic's Joe Buscaglia, McDermott also said that the disciplinary action stemmed from an incident in practice, and that the Bills "expect more" from the second-year wideout. Coleman recorded four catches for 23 yards and a touchdown on seven targets in Week 5. For the season, he's hauled in 21 catches for 226 yards and two scores on 29 targets. It doesn't seem as though this incident will impact Coleman's playing time going forward, but it's still not a good sign for the 22-year-old. He profiles as a fantasy WR3/flex option heading into a Week 6 matchup with the Atlanta Falcons.

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New York Giants wide receiver Darius Slayton (hamstring) was listed as a non-participant in practice on Monday's injury report. Slayton left late in New York's Week 5 loss to the New Orleans Saints with a hamstring injury and did not return. The Giants have a short week in Week 6 as they prepare to take on the Philadelphia Eagles on Thursday night, so it could be tough for Slayton to recover in time to play. The 28-year-old recorded three catches for 31 yards on six targets before getting hurt in New York's first full game without star wideout Malik Nabers (knee). If Slayton is sidelined for Week 6, Giants wide receivers Wan'Dale Robinson and Jalin Hyatt would likely see an uptick in targets.

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Former Tennessee Titans wide receiver Treylon Burks (collarbone) has been cleared for all football activities and is free to sign with any team, per Ian Rapoport of NFL Network. Burks suffered a broken collarbone in training camp and was subsequently released by the Titans while on Injured Reserve. A former first-round pick by Tennessee in 2022, Burks recorded 53 catches for 699 yards and a touchdown in 27 games across three injury-filled seasons for the Titans. He's currently a long way from fantasy relevance, but Burks could be a name to monitor if he catches on with a new team.

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New York Giants running back Tyrone Tracy Jr. (shoulder) was listed as a limited practice participant on Monday's injury report. Tracy Jr. dislocated his shoulder in Week 3 and has missed each of the Giants' last two games, but he was reportedly making good progress ahead of Week 5. Tracy Jr. could be available on Thursday night, when the Giants take on the Philadelphia Eagles in the opening game of Week 6. Rookie running back Cam Skattebo has taken over as New York's lead running back in Tracy Jr.'s absence, recording 194 yards from scrimmage on 48 total touches over the last two weeks. Once Tracy Jr. returns, the two backs should be expected to split touches, but Skattebo may remain the team's lead rusher.

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Dynasty | Patriots running back Antonio Gibson will miss the rest of the season with a torn ACL. Dynasty Analysis: It's a tough break for Gibson, who was quickly carving out a role in what was a terrific committee in reality and terrible one in fantasy as Rhamondre Stevenson and TreVeyon Henderson are still in the mix. Gibson's injury is going to make him a really tough hold in dynasty leagues, despite him being productive when healthy. In essence, he's a bit of a roster clogger.

Minnesota Vikings QB J.J. McCarthy (ankle) is expected to be at least a limited participant during practice next week, according to head coach Kevin O'Connell.

Dynasty | Cowboys wide receiver Ryan Flournoy had six catches for 114 yards in a win against the Jets. Dynasty Analysis: Wait. What? Flournoy surpassed 100 yards in the first half alone this week and cruised to a career high on the day. He tied Jake Ferguson for the team lead in targets with nine and looked like a player who has progressed quite nicely over the past year or two. With CeeDee Lamb and Kevontae Turpin both out with injuries, you could say he took advantage of his opportunity. We'll need to see a lot more from him moving forward in order to recommend him but he could move up to the WR3 spot in Dallas behind Lamb and George Pickens if he continues to play well. At this point, he simply looks like a solid waiver wire pickup and roster stash.

Dynasty | Panthers running back Rico Dowdle had 206 rushing yards, three catches, 28 receiving yards and a touchdown in a win against Miami. Dynasty Analysis: Dowdle was solid for Dallas last year but they moved on from him this off-season, forcing him to sign a deal with the Panthers to back up Chuba Hubbard. With Hubbard out with an injury this week, Dowdle took over the backfield and simply annihilated Miami. Had it not been for some late game cramps, he would have set the all-time record for rushing yards in franchise history (210 is the record set by DeAngelo Williams). This performance is likely going to create a bit of a timeshare moving forward when Hubbard returns which could prove to be great for the Panthers but awful in fantasy football. Regardless, Dowdle will be a must-start next week in a #revenge game against Dallas should Hubbard sit out again.

Dynasty | Bucs rookie wide receiver Emeka Egbuka had seven catches for 163 yards and a touchdown in a win against Seattle. Dynasty Analysis: It just gets better every week with Egubka, who is now up to 25 catches for 445 yards and five scores on the year. It's been a fascinating start for the former Ohio State star, who clearly looks like a star already, not just a star in the making. All the talk this off-season was about Ashton Jeanty being the unquestioned top rookie and the debate between Tetairoa McMillan and Travis Hunter being the top receiver. In the end, Egbuka looks like the single best rookie in the draft at this point. If you benefitted from him falling to you, congratulations.

Dynasty | Seahawks tight end AJ Barner had seven catches for 53 yards and two touchdowns in a loss to Tampa Bay. Dynasty Analysis: Barner has made Elijah Arroyo irrelevant so far this season and now has four touchdowns on the year. It's been a quick rise for Barner who is clearly looking like a player who is going to garner lineup consideration moving forward. The buying window likely closed with this performance as Barner really does look like a legitimate weapon in fantasy football with Seattle's offense playing this well.

Dynasty | Cardinals running back Michael Carter had 51 rushing yards, five catches, 22 receiving yards, and one touchdown in a loss to the Titans. Dynasty Analysis: Carter had said earlier in the week that he was going to be the starter taking over for Trey Benson (who had subsequently taken over for James Conner) and that proved to be the case as he had 18 of the 25 carries by running backs and five of the six catches as well. Emari Demercado had the play of the game in just about every way as he busted a 71-yard run but spoiled it by dropping the ball before crossing the goal line. Carter should keep the job moving forward and could make for a solid short-term starter or rental for contending dynasty teams.

Tennessee Titans running back Tyjae Spears made his return in Week 5 from a high ankle that kept him out for the first four games of the season. Spears saw limited usage in his first game back, playing 17 total snaps and recording four carries for 14 yards against the Arizona Cardinals. However, Titans head coach Brian Callahan said Spears' role will increase in future weeks, per Jim Wyatt of TennesseeTitans.com. The 24-year-old recorded 536 yards from scrimmage and five touchdowns on 114 total touches across 12 games last season. Spears and Titans back Tony Pollard will split backfield work to some degree once Spears is fully healthy and re-integrated into the offense. For now, Spears should be rostered by fantasy managers, but likely cannot be trusted as a starter in Week 6 against the Las Vegas Raiders.

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