San Francisco 49ers quarterback Jimmy Garoppolo (10) passes against Seattle Seahawks defensive tackle Quinton Jefferson (99) during the second half of an NFL football game in Santa Clara, Calif., Monday, Nov. 11, 2019. (AP Photo/Tony Avelar)
Arizona Cardinals quarterback Kyler Murray (1) throws a pass against the Tampa Bay Buccaneers during the first half of an NFL football game Sunday, Nov. 10, 2019, in Tampa, Fla. (AP Photo/Jason Behnken)
SANTA CLARA, Calif. (AP) After nothing but success the first eight games of the season, the San Francisco 49ers now are learning to deal with failure.
The Niners' perfect season was derailed last week with an overtime loss to the Seattle Seahawks when San Francisco was unable to overcome a litany of offensive miscues.
The 49ers (8-1) will look to get back on the winning track Sunday when they host the Arizona Cardinals (3-6-1) for the second time in three weeks.
''I think we have a good mindset with it,'' said quarterback Jimmy Garoppolo, who had his worst day of the season in the 27-24 loss. ''Everyone was in here yesterday working on the day off. Today it's just a sense of urgency in the building. It's good to see that.''
San Francisco committed three turnovers, allowed five sacks and struggled to get much of anything going consistently on the ground or through the air against Seattle.
The 49ers had season lows in yards rushing (87) and yards per attempt passing (4.7) on a night that star tight end George Kittle was out with an injury and No. 1 receiver Emmanuel Sanders left with injured ribs in the first quarter.
San Francisco is using that performance as a teaching tool for the rest of the season.
''You learn from the good and you learn more from the bad,'' tackle Mike McGlinchey said. ''It's a huge step in the right direction for us to be able take as many blows as we did and play as poorly as we did and still have a chance, not only one chance but multiple chances to win that game. That's a testament to how our defense played. ... We need to do a better job on the offensive side of the ball to make sure we reward their work.''
The Cardinals are stumbling toward their bye week, having lost three straight games after a promising start to the first season under coach Kliff Kingsbury and rookie quarterback Kyler Murray.
One of those losses was two weeks ago when Arizona fell 28-25 at home to the 49ers, a performance that gives the Cardinals confidence that if they can fix some mistakes they can compete with the first-place Niners.
''I don't think we played our best game,'' Murray said. ''I know personally, if we just go out and execute - they know what we do, we know what they do - if we go out and execute, we should be in good shape.''
The Niners' offense was done in by the absence of Kittle and Sanders last week. San Francisco scored 10 points on the opening two drives when Sanders was healthy and then just six more on offense the rest of the game. With no consistent receiving threats, the Seahawks were able to load up against the run and allow only 3.2 yards per carry. Kendrick Bourne had two key drops for San Francisco, while Dante Pettis and Marquise Goodwin combined for no catches on six targets.
Arizona has relied on a variety of playmakers this season and the latest to make big plays is rookie receiver Andy Isabella. The second-round pick out of UMass had an 88-yard touchdown catch against the 49ers in the first meeting between the teams on Oct. 31. He has six catches for 174 yards over the past three games after not even being targeted in the season's first seven games. Kingsbury said Isabella has been improving steadily all season.
''It's been trending that way for a while,'' he said. ''We've had him inside, had him outside, and I think now the comfort level, having him outside more so, has really helped his development recently.''
MAN IN THE MIDDLE
The defensive star of the game for the 49ers last week was middle linebacker Fred Warner, who stepped up his performance in his first game since fellow starting linebacker Kwon Alexander suffered a season-ending torn pectoral muscle. Warner had 10 tackles, the first two sacks of his career, one forced fumble and a pass defensed.
''He gets us in and out of everything,'' coach Kyle Shanahan said. ''He has to make a ton of calls. He's definitely our quarterback out there and I think he does it as good as anyone I've seen.''
Arizona's defense ranks 31st out of 32 teams in points allowed (281), total yards allowed per game (412.5) and passing yards allowed per game (286.5). The Cardinals have given up at least 21 points in all 10 games this season but never have given up more than 38. Linebacker Chandler Jones has been one of the bright spots with 11 1/2 sacks and five forced fumbles. Three-time All-Pro cornerback Patrick Peterson returned from a six-game suspension last month but hasn't had much of an impact. Kingsbury said the Cardinals had bouts of poor tackling in last week's 30-27 loss to Tampa Bay.
''There were some shoulders being thrown,'' Kingsbury said. ''We have to be better in those situations.''
The 49ers again will be without starting left tackle Joe Staley, who will be out a couple of weeks after undergoing surgery on a broken finger. Staley broke a bone in his leg in Week 2 and missed the next six games. He then got hurt in his return to the lineup. With Staley unable to go, rookie Justin Skule is expected to move back into the lineup.
''I thought he did a very good job,'' Shanahan said of Skule. ''He came in there and stepped it up right away. Did a good job in his first game and I thought he got better each week.''
Houston Texans CB Gareon Conley (hip) is expected to play in Week 14's game against the Denver Broncos, according to a source. He had been listed as questionable on the injury report after being a limited practice participant throughout the week.
Houston Texans CB Bradley Roby (hamstring, toe) is expected to play in Week 14's game against the Denver Broncos, according to a source. He had been listed as questionable on the injury report after being a limited practice participant throughout the week.
The Tennessee Titans are reportedly discussing a contract extension for quarterback Ryan Tannehill. Since taking over for Marcus Mariota as the team's starting passer in Week 7, Tannehill has been putting up solid numbers, with 12 touchdown passes and three interceptions while completing 71.9 percent of his passes. He's also rushed for three scores. Tannehill appears to be a solid starting quarterback going forward, and with the Titans not bad enough to draft a top quarterback in the upcoming draft, it makes sense to extend him. He's a solid fantasy QB2 with QB1 upside depending on the matchup.
Cleveland Browns WR Odell Beckham Jr. (groin) has been playing through a painful sports hernia injury this year which will require surgery during the offseason, according to multiple sources.
Fantasy Spin: The 27-year-old Beckham has 57 receptions for 805 yards and just two touchdowns through the first 12 games of the season. As a result of the injury, he has missed a great deal of practice time, which could explain why he and QB Baker Mayfield often appear as though they're not on the same page. Despite the sports hernia issue, Beckham will continue to receive a decent number of targets in the Cleveland passing game and should be viewed as a low-end WR1 or high-end WR2 in fantasy leagues.
The Los Angeles Rams plan to unleash running back Todd Gurley over the last four weeks of the season, giving him a full workload as the team tries to bolster their chances of making the postseason. Gurley's played two games this year with a snap rate of 90 percent or better, though his yardage and yards per carry in those games weren't great. There's still risk with Gurley, but he should be a solid RB1 if the Rams do give him the majority of their running back touches.
Updating a previous report, Minnesota Vikings WR Adam Thielen (hamstring) will probably miss Week 14's game versus the Detroit Lions but has a good chance of returning for Week 15's game against the Los Angeles Chargers.
Fantasy Spin: Thielen is a must-start option when healthy, although he has not played a full game since Week 6 and hasn't played at all since Week 9. Fantasy owners should keep him on the bench this week and look for safer receiving alternatives.
New England Patriots WR Julian Edelman (shoulder) is expected to play in Week 14's game against the Kansas City Chiefs, according to a source.
Fantasy Spin: Edelman was listed as questionable on the injury report after being a limited practice participant throughout the week. He is the main target in New England's passing game and is worthy of consideration as at least a No. 2 fantasy receiver this afternoon.
New England Patriots WR Mohamed Sanu (ankle) is expected to play in Week 14's game against the Kansas City Chiefs, according to a source.
Fantasy Spin: Sanu was listed as questionable on the injury report after being a limited practice participant throughout the week. He could be a decent flex option in most fantasy formats this afternoon because this has the potential to be a high-scoring game and he's likely to be targeted more frequently than normal.
Baltimore Ravens CB Marlon Humphrey (thigh) is expected to play in Week 14's game against the Buffalo Bills, according to a source. He had been listed as questionable on the injury report after logging two limited practice sessions and one full session during the week.
Minnesota Vikings WR Adam Thielen (hamstring) is not expected to play in Week 14's game against the Detroit Lions, according to a source.
Fantasy Spin: Thielen had been listed as doubtful on the injury report after not practicing at all during the week and it appears as though he will be sidelined for the fifth time in the last six games. Fantasy owners should keep him stashed on their benches this afternoon and look for alternative options.
Houston Texans WR Will Fuller (hamstring) is not expected to play in Week 14's game against the Denver Broncos, according to a source.
Fantasy Spin: Fuller was listed as questionable on the injury report after being a limited practice participant throughout the week. When healthy, he makes a decent flex option but fantasy owners should keep him stashed on their benches this week and proceed with safer alternatives.
Denver Broncos LB Von Miller (knee) is expected to play in Week 14's game against the Houston Texans, according to a source. He had been listed as questionable on the injury report after being a limited practice participant throughout the week.
New York Jets S Jamal Adams (ankle) is not expected to play in Week 14's game against the Miami Dolphins, according to a source. He had been listed as doubtful on the injury report after not practicing at all during the week.
Cleveland Browns wide receiver Odell Beckham Jr. is playing through a painful sports hernia injury, according to NFL.com's Ian Rapoport. The star receiver will need to have offseason surgery to repair the injury. While it hasn't caused Beckham to miss any games, the injury has cut into his practice time and can be one of the reasons why he and Baker Mayfield have struggled with their on-field rapport this season. For now, it appears that Beckham will finish out the season but there is a risk of him getting shut down early if the Browns fall out of playoff contention.
Minnesota Vikings wide receiver Adam Thielen (hamstring) is expected to be out against the Lions in Week 14. Thielen suffered the injury at the end of October and will likely miss his fourth straight after failing to log a practice this week. In his absence, expect more looks for Stefon Diggs, Kyle Rudolph, and Alexander Mattison on Sunday.
New England Patriots wide receiver Julian Edelman (shoulder) is expected to be available for the critical matchup with Kansas City on Sunday. Edelman has been dealing with the ailment for quite some time but has been able to play. He has logged at least 11 targets in each of his last seven games and should continue to get plenty of looks from Tom Brady in Week 14 despite Mohamed Sanu (ankle) also expected to see the field. Keep him starting in all fantasy formats.
Houston Texans wide receiver Will Fuller (hamstring) is not expected to play against Denver on Sunday. After playing against the Pats in Week 13, Fuller will probably miss his fourth game of the year after suffering another setback. While this isn't a massive blow to fantasy owners, especially considering the matchup against a relatively tough Broncos Defense, it isn't good news for those in deeper fantasy formats. Expect Kenny Stills to serve as the primary beneficiary in Week 14.
Oakland Raiders running back Josh Jacobs (shoulder) may not play against Tennessee on Sunday, with his status for Week 14 still up in the air. Jacobs has carried this designation over the last five weeks, and while he has been able to suit up during that span, this may be the first time that Oakland is without him this year. He was able to practice on Friday in a limited capacity after missing the previous two sessions, but if he is out, expect Deandre Washington to carry the load as the No. 1 option out of the backfield against an average Titans Defense. Keep an eye on his availability up until kickoff.
Baltimore Ravens wide receiver Marquise Brown (ankle) is expected to play on Sunday in Buffalo. Hollywood has been dealing with this issue for the majority of the year, so his designation throughout the week wasn't a huge surprise. The rookie fizzled in Week 13 against the 49ers after accounting for two touchdowns against the Rams in Week 12, and while the upside is there, he draws a tough matchup against a Bills Defense that is ranked in the top-six against opposing wideouts this season. Proceed with caution.
Pittsburgh Steelers WR James Washington has had a reception of 30-plus yards in four of the last five games and has recorded at least 90 receiving yards and a touchdown in three of the last four games.
Fantasy Spin: Despite Pittsburgh's quarterback carousel, Washington has emerged as a dangerous deep threat. He's a big-play dependent but high-upside WR3 against the Arizona Cardinals in Week 14.