Guest of the League
Lineup Changes
As Good As It Betts. - Jason Rosenberg
| Benched | Jordan Hicks (P) SF | Owner | Mon May 6 1:38am ET |
| Started P | John Means (P) BAL | Owner | Mon May 6 1:38am ET |
| Started P | Cole Irvin (P) BAL | Owner | Mon May 6 1:36am ET |
| Started P | Walker Buehler (P) LAD | Owner | Mon May 6 1:35am ET |
Ballbusters 75 - Joseph Solomon
| Started OF | Eloy Jimenez (OF) CWS | Owner | Mon May 6 12:57pm ET |
| Benched | Joe Musgrove (P) SD | Owner | Sun May 5 9:25pm ET |
| Started P | Nick Pivetta (P) BOS | Owner | Sun May 5 9:25pm ET |
| Benched | Nathan Eovaldi (P) TEX | Owner | Fri May 3 7:46pm ET |
| Started P | Joe Musgrove (P) SD | Owner | Fri May 3 7:46pm ET |
Between the Lines - Steve Yingling
| Started P | Paul Blackburn (P) OAK | Owner | Mon May 6 1:50am ET |
| Started P | Jack Flaherty (P) DET | Owner | Mon May 6 1:50am ET |
| Started P | Yu Darvish (P) SD | Owner | Mon May 6 1:50am ET |
| Started P | Craig Kimbrel (P) BAL | Owner | Thu May 2 12:03am ET |
| Benched | Grayson Rodriguez (P) BAL | Owner | Thu May 2 12:03am ET |
BOMBS - Kevin Hagen
| Started OF | Josh Lowe (OF) TB | Owner | Mon May 6 5:40pm ET |
| Benched | Randy Arozarena (OF) TB | Owner | Mon May 6 5:40pm ET |
| Started P | Dean Kremer (P) BAL | Owner | Mon May 6 11:19am ET |
| Benched | Zac Gallen (P) ARI | Owner | Mon May 6 11:19am ET |
| Started P | Zac Gallen (P) ARI | Owner | Mon May 6 6:43am ET |
| Started OF | Randy Arozarena (OF) TB | Owner | Mon May 6 6:42am ET |
| Benched | Jackson Chourio (OF) MIL | Owner | Mon May 6 6:42am ET |
| Started SS | Luis Rengifo (2B, SS, 3B, OF) LAA | Owner | Mon May 6 6:42am ET |
| Benched | Trea Turner (SS) PHI | Owner | Mon May 6 6:42am ET |
| Started P | Robert Suarez (P) SD | Owner | Sun May 5 3:48pm ET |
| Benched | Reynaldo Lopez (P) ATL | Owner | Sun May 5 3:48pm ET |
| Benched | Evan Phillips (P) LAD | Owner | Sun May 5 3:48pm ET |
| Started P | Edwin Diaz (P) NYM | Owner | Sun May 5 3:48pm ET |
| Benched | Robert Suarez (P) SD | Owner | Sat May 4 10:43pm ET |
| Started P | Reynaldo Lopez (P) ATL | Owner | Sat May 4 10:43pm ET |
| Benched | Edwin Diaz (P) NYM | Owner | Sat May 4 10:42pm ET |
| Started P | Jhoan Duran (P) MIN | Owner | Sat May 4 10:42pm ET |
| Started P | Kyle Bradish (P) BAL | Owner | Sat May 4 10:42pm ET |
| Benched | Reynaldo Lopez (P) ATL | Owner | Sat May 4 10:42pm ET |
| Started OF | Jackson Chourio (OF) MIL | Owner | Fri May 3 12:01am ET |
| Benched | Randy Arozarena (OF) TB | Owner | Fri May 3 12:01am ET |
CharlieHustle - Jerry Deaton
| Started OF | Evan Carter (OF) TEX | Owner | Mon May 6 6:29pm ET |
| Benched | Tyler O'Neill (OF) BOS | Owner | Mon May 6 6:29pm ET |
| Benched | Evan Carter (OF) TEX | Owner | Mon May 6 6:29pm ET |
| Started U | Vinnie Pasquantino (1B) KC | Owner | Mon May 6 6:29pm ET |
| Benched | Nick Lodolo (P) CIN | Owner | Mon May 6 3:07pm ET |
| Started P | Triston McKenzie (P) CLE | Owner | Mon May 6 3:07pm ET |
| Started SS | Jose Caballero (2B, SS) TB | Owner | Mon May 6 3:05pm ET |
| Benched | Orlando Arcia (SS) ATL | Owner | Mon May 6 3:05pm ET |
| Started 2B | Bryson Stott (2B) PHI | Owner | Mon May 6 12:08am ET |
| Benched | Justin Turner (1B, 2B) TOR | Owner | Mon May 6 12:08am ET |
| Benched | Michael Busch (1B, 3B) CHC | Owner | Mon May 6 12:06am ET |
| Started 3B | Rafael Devers (3B) BOS | Owner | Mon May 6 12:06am ET |
| Started U | Evan Carter (OF) TEX | Owner | Mon May 6 12:06am ET |
| Benched | Rafael Devers (3B) BOS | Owner | Mon May 6 12:06am ET |
D Supernatural1 - Reicher Sinco
| Benched | Ronel Blanco (P) HOU | Owner | Mon May 6 2:59am ET |
| Started P | Jon Gray (P) TEX | Owner | Mon May 6 2:59am ET |
| Started 2B | Brice Turang (2B, SS) MIL | Owner | Mon May 6 2:52am ET |
| Started 1B | Jake Cronenworth (1B, 2B) SD | Owner | Mon May 6 2:52am ET |
| Benched | Mark Canha (1B, OF) DET | Owner | Mon May 6 2:52am ET |
| Benched | Jake Cronenworth (1B, 2B) SD | Owner | Mon May 6 2:52am ET |
| Benched | Brice Turang (2B, SS) MIL | Owner | Mon May 6 2:46am ET |
| Started SS | Corey Seager (SS) TEX | Owner | Mon May 6 2:46am ET |
| Started P | Bryce Miller (P) SEA | Owner | Mon May 6 2:37am ET |
| Started P | Logan Allen (P) CLE | Owner | Mon May 6 2:37am ET |
| Benched | Jon Gray (P) TEX | Owner | Mon May 6 2:37am ET |
DB CAVS - Joe Morrow
| No starting lineup changes performed this week. |
floydios -
| Started 3B | Josh Rojas (2B, 3B) SEA | Owner | Mon May 6 1:00pm ET |
| Started 1B | Jon Singleton (1B) HOU | Owner | Mon May 6 10:55am ET |
| Benched | Freddie Freeman (1B) LAD | Owner | Mon May 6 10:55am ET |
| Benched | Emmanuel Clase (P) CLE | Owner | Mon May 6 10:42am ET |
| Started P | Kyle Gibson (P) STL | Owner | Mon May 6 10:42am ET |
| Benched | Ke'Bryan Hayes (3B) PIT | Owner | Mon May 6 10:37am ET |
| Started 3B | Willi Castro (2B, SS, 3B, OF) MIN | Owner | Mon May 6 10:37am ET |
| Started P | Cole Ragans (P) KC | Owner | Mon May 6 8:02am ET |
| Benched | Martin Perez (P) PIT | Owner | Mon May 6 8:02am ET |
| Benched | Steven Kwan (OF) CLE | Owner | Mon May 6 8:02am ET |
| Started OF | Jarren Duran (OF) BOS | Owner | Mon May 6 8:02am ET |
Longballerz - Joseph Re
| Started OF | Tommy Pham (OF) CWS | Owner | Mon May 6 11:34am ET |
| Started OF | Jo Adell (OF) LAA | Owner | Mon May 6 11:29am ET |
| Benched | Joe Ryan (P) MIN | Owner | Mon May 6 2:02am ET |
| Started P | George Kirby (P) SEA | Owner | Mon May 6 2:02am ET |
| Benched | Jordan Montgomery (P) ARI | Owner | Mon May 6 2:01am ET |
| Started P | Kirby Yates (P) TEX | Owner | Mon May 6 2:01am ET |
| Benched | Brandon Pfaadt (P) ARI | Owner | Mon May 6 2:01am ET |
| Started P | Justin Steele (P) CHC | Owner | Mon May 6 2:01am ET |
| Started P | Luis Castillo (P) SEA | Owner | Mon May 6 2:01am ET |
| Benched | Marcus Stroman (P) NYY | Owner | Mon May 6 2:01am ET |
Nokahoma 2 - Wendell Richardson
| Started OF | Brent Rooker (OF) OAK | Owner | Mon May 6 10:46am ET |
| Benched | Luis Severino (P) NYM | Owner | Mon May 6 10:36am ET |
| Started P | Luis Gil (P) NYY | Owner | Mon May 6 10:36am ET |
| Started P | Tyler Anderson (P) LAA | Owner | Mon May 6 10:36am ET |
