Boston Red Sox first baseman Willson Contreras (illness) was removed early from his team's game against the Chicago White Sox on Wednesday due to an illness, per Chris Cotillo of MassLive. Contreras was one-for-one with an RBI and a walk before exiting the game. The 34-year-old has put together an excellent season so far in 2026, hitting .288/.395/.540 with 23 home runs, 70 RBI, 57 runs scored, and three stolen bases across 430 plate appearances. In his 11th MLB season, he's posted his best barrel rate (14.5%). It's not totally clear what the illness that Contreras is battling is, but it seems unlikely that he is looking at significant missed time. Red Sox infielder Anthony Seigler replaced Contreras on Wednesday, and both he and utility man Nick Sogard are candidates to see more playing time if Contreras needs to miss a day or two.

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Newly acquired San Diego Padres starting pitcher Casey Mize is making his debut with the team on Wednesday against the Arizona Diamondbacks. The Padres acquired Mize from the Detroit Tigers on Monday in exchange for pitching prospects Kash Mayfield and Jackson Wolf. Mize has had a strong season so far in 2026, recording a 4-6 record with a 2.70 ERA, 0.99 WHIP, and 85 strikeouts cross 86 2/3 innings (14 starts). The 29-year-old has also needed multiple stints on the injured list due to groin strains, but he's healthy now and will be relied upon as a key piece in the Padres rotation down the stretch. Mize has posted the best K-BB rate (19.4%) of his career this year, and he's limited hard contact with a 0.52 HR/9. When healthy, he profiles as a must-start fantasy pitcher in most league formats.

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Seattle Mariners President of Baseball Operations Jerry Dipoto said that top pitching prospect Kade Anderson will be part of the team's starting rotation once he's called up to the big leagues, per Adam Jude of The Seattle Times. Jude reports that Anderson is expected to be promoted from Double-A Arkansas "in the coming weeks." Anderson is widely considered to be one of the top prospects in all of baseball and has put together a dominant season in the minor leagues. Across 82 2/3 innings (16 starts), the young left-hander has recorded a 9-1 record with a 1.20 ERA, 0.66 WHIP, and 119 strikeouts. He's posted an absurd 40.5% strikeout rate with just a 4.1% walk rate. Once Anderson gets called up, he offers serious upside for fantasy managers.

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Chicago Cubs outfielder Pete Crow-Armstrong went toe-to-toe with four-time MVP Shohei Ohtani and the Los Angeles Dodgers in Wednesday's 7-6 win at Wrigley Field. Both Crow-Armstrong and Ohtani hit two home runs apiece, with Crow-Armstrong going 3-for-5 in the leadoff spot with four RBI and a strikeout. After a slow start to the 2026 campaign, the 24-year-old left-handed slugger has been heating up since June. The two-time All-Star came into Wednesday's action with a .284/.384/.535 slash line with a .919 OPS, 24 home runs, 65 RBI, 28 stolen bases, and 76 runs scored across 426 at-bats. Crow-Armstrong has now gone 7-for-17 with two home runs, a double, a triple, six RBI, and seven runs scored in his first five games in August as he continues to stay locked in at the dish. He's now up to three multi-homer games in 2026 and nine for his career. While PCA's numbers look great, his .257 xBA and .364 xwOBA predict regression to close out the campaign.

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Los Angeles Dodgers designated hitter Shohei Ohtani had his first multi-home run game of the season in Wednesday's 7-6 loss to the Chicago Cubs at Wrigley Field, going 3-for-5 at the plate with two home runs, three RBI, and two strikeouts to boost his season average to .297 and his OPS to .953. Ohtani's first home run came to lead off the game against lefty starter Shota Imanaga, and his second blast came in the eighth inning off new Cubs reliever Ryan Zeferjahn, but the Dodgers ultimately fell one run short. It's a bit hard to believe that the four-time MVP and six-time All-Star didn't have a multi-homer game this year until Aug. 5. Ohtani continues to serve as the Dodgers' regular DH despite having not pitched since July 3 due to a nagging knee and biceps issue. His knee issue hasn't really affected Ohtani as a hitter at all, as he's now gone 15-for-31 in his last eight games, and he's up to 26 home runs with a .953 OPS in 2026 in his ninth year in the big leagues. It doesn't look like the Japanese superstar is going to reach the 50-homer mark for a third straight year, and he's barely running (six steals), but he remains a must-start in all traditional fantasy formats as a hitter.

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The Athletic's Dan Hayes reports that Minnesota Twins right-hander Joe Ryan's (back, glute) next start is "in doubt" due to back and glute injuries. Manager Derek Shelton said that Ryan has already left the team to be evaluated by team physician Christopher Camp in Minneapolis. "He's frustrated and not able to replicate his delivery. The ability to repeat his delivery, I'm not going to say it's not physical. But we owe it to him and to us to find out what he's feeling and how he's going about it," Shelton said. Ryan allowed four earned runs in 5 1/3 innings in Tuesday's loss to the division-rival Kansas City Royals, and when asked if he's physically capable of doing what he wants with his delivery, Ryan said, "No, definitely not." It helps explain why he has a 9.39 ERA with 25 hits allowed in 15 1/3 frames in his last three outings. He also gave up a major-league record six home runs on July 20 against the division-rival Cleveland Guardians. Ryan was dominant for fantasy managers in the first half, posting a 2.85 ERA with 128 strikeouts in 110 1/3 innings, but he has fallen apart in the second half and just isn't healthy right now. It sounds like an injured-list stint is coming.

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The Arizona Diamondbacks have activated catcher Gabriel Moreno from the paternity list on Wednesday, and he will serve as the designated hitter and bat cleanup against the San Diego Padres and right-hander Casey Mize, who will be making his debut with the Friars. James McCann will do the catching and bat seventh for the Snakes. Moreno will end up missing just one game on Tuesday to catch the birth of his second child this week. The 26-year-old Venezuelan backstop is having a fine season at the plate in 85 games (350 plate appearances), slashing .298/.380/.438 with a career-high .818 OPS, eight home runs, 47 RBI, 46 runs scored, and four stolen bases in his fifth year in the majors (fourth in Arizona). Moreno is coming off a great month of July, too, in which he hit .362 (34-for-94) with two home runs, six doubles, 19 RBI, and 18 runs scored in 25 games played.

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Milwaukee Brewers first baseman/outfielder Jake Bauers (abdomen) is out of the team's starting lineup for the second straight day on Wednesday against the division-rival Pittsburgh Pirates due to an abdominal injury, per MLB.com. Andrew Vaughn will make another start at first base and will hit sixth for the Brewers against Pirates right-hander Paul Skenes. Bauers should be considered day-to-day for now after taking part in some on-field workouts before Wednesday's game at American Family Field. He could be back for fantasy managers as soon as Thursday's series finale against the Pirates. The 30-year-old left-handed slugger is in the midst of a career breakout in 2026 in his seventh year in the big leagues (third with Milwaukee), slashing .270/.375/.503 with an .878 OPS, 20 home runs, 64 RBI, 68 runs scored, and eight stolen bases across 102 games and 403 plate appearances. Most of Bauers' damage this year has come against right-handed pitchers, which is not a major surprise. He has hit just three of his 20 round-trippers on the year against lefties.

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The Cincinnati Reds announced on Wednesday that they placed right-hander Hunter Greene (elbow) on the 15-day injured list (retroactive to Aug. 2) with soreness in his right elbow and recalled right-hander Luis Mey from Triple-A Louisville in a corresponding move. Per C. Trent Rosecrans of The Athletic, Greene will visit with Dr. Neal ElAttrache in Los Angeles on Thursday after feeling discomfort in his elbow during a side session on Tuesday. The hard-throwing right-hander underwent an MRI exam on Wednesday morning. The 26-year-old former second overall pick in 2017 has only made five starts for the Reds in 2026 after already recovering from a procedure on his right elbow. Greene has been up and down in his 27 2/3 innings so far this year, recording a 6.83 ERA (3.57 FIP) and 1.37 WHIP with 33 strikeouts and only nine walks. A visit to ElAttrache is not what fantasy managers want to hear, as it could result in another surgery for Greene. For now, he should remain stashed in leagues where he's rostered.

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New York Yankees manager Aaron Boone said that outfielder Aaron Judge (rib) has been "cleared" to start "light" activities, including running and upper-body "resistance" work in the weight room, according to Erik Boland of Newsday. It represents significant progress from where Judge had been while rehabbing a stress fracture of the first rib on his right side since June 5. Judge is currently on the 60-day injured list without a timetable for a return, but fantasy managers have to be a little excited with this update on his progress, even though he still has plenty of boxes to check before returning to the big-league lineup. The Yankees are optimistic that the three-time MVP will return before the season is over, but fantasy managers probably won't be getting him back until the final month of the regular season in September in a best-case scenario. In an attempt to bolster the Yankees' offense with Judge, Cody Bellinger, and Giancarlo Stanton on the IL, the team traded for infielder Luis Garcia Jr. and outfielder Heliot Ramos at the deadline this summer.

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Los Angeles Dodgers first baseman Freddie Freeman (wrist) left Wednesday's game against the Chicago Cubs at Wrigley Field early due to an apparent wrist injury after a check swing in the top of the fifth inning, according to Dodgers writer Adrian Medina. Freeman went 1-for-3 at the plate before being replaced at first base by Enrique Hernandez. It's unclear how serious Freeman's injury is, but the Dodgers will not take any chances with their star players with a huge cushion in the National League West right now. The 36-year-old former MVP, 10-time All-Star, and World Series MVP is the heartbeat of the Dodgers, other than two-way Superstar Shohei Ohtani, so losing him for an extended period of time would be a major blow to L.A.'s core. Freeman came into Wednesday's contest with a strong .310/.385/.486 slash line, .871 OPS, 15 home runs, 54 RBI, 57 runs scored, and five steals in his 420 at-bats. If Freeman were to miss additional time, both Hernandez and Max Muncy would be options to take over at first base for the Blue. Hopefully, Freeman will be ready to return for Friday's series opener against the division-rival Arizona Diamondbacks after a scheduled off day on Thursday.

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Cleveland Guardians third baseman Jose Ramirez (hand) will miss a second straight game due to a sore hand on Wednesday in the team's matchup against the visiting New York Mets, according to MLB.com. Rookie infielder Angel Genao will make the start at the hot corner for Cleveland and will hit in the nine-hole against Mets right-hander Christian Scott. Ramirez was out of action on Tuesday due to soreness in his surgically-repaired left hand. The 33-year-old Dominican veteran and seven-time All-Star missed extended time already this year following surgery to fix a fractured hamate bone in his left hand, so it's bad news that he's still dealing with discomfort. J-Ram hasn't looked comfortable at the plate since his return on July 22, going 8-for-41 (.195) with a .478 OPS, zero homers, two RBI, three steals, six runs scored, five walks, and two strikeouts in just 10 games played. Don't be surprised if Ramirez lands back on the IL, which would be another tough break in what has been a bust of a season for the perennial MVP candidate. He's hitting just .233/.331/.388 with a .720 OPS, 10 homers, 35 RBI, 27 steals, and 48 runs scored in his 82 games played in his 14th year in the majors.

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In his major-league debut on Tuesday against the St. Louis Cardinals, New York Yankees infield prospect George Lombard Jr. went 1-for-2 at the plate with a solo home run and a walk in the 2-0 victory. The 21-year-old hit eighth in his first MLB game as he takes over at the 6 in the Bronx for Anthony Volpe, who was demoted to Triple-A Scranton/Wilkes-Barre. The Yankees' top prospect, per MLB Pipeline, also made a difference with his glove in his MLB debut, and he is expected to help give the team a boost down the stretch. Lombard's power/speed upside makes him immediately attractive in most fantasy baseball leagues, and he's already rostered in 38% of Yahoo setups. The former 26th overall pick in the 2023 MLB draft hit .284/.411/.498 with a .909 OPS, 12 home runs, 33 RBI, 14 stolen bases, and 65 runs scored in 78 games (358 plate appearances) in the rookie-level Florida Complex League and at Double-A Somerset and Triple-A. Don't expect a ton of power from Lombard, with his above-average speed and on-base skills likely to benefit fantasy managers first.

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A viral Reddit post claims to reveal the alleged story behind the fallout between Boston Red Sox outfielder Roman Anthony and infielder Marcelo Mayer that ultimately led to Mayer being traded to the San Francisco Giants at the deadline on Monday, according to What's the Word? Anthony reportedly suffered the finger/wrist injury that has kept him out for most of the season during an altercation with Mayer over a conflict of interest with a woman. Both Anthony and Mayer, who came up through the farm system as two of Boston's top prospects, have failed to deliver early in their big-league careers, but injuries certainly haven't helped their cause. Anthony is the much better upside stash in fantasy baseball leagues for his power/speed upside, while the 23-year-old Mayer could find himself in a platoon role in his new home in San Fran whenever he gets healthy. Mayer has been out since June 26 with a stress reaction in his left forearm, and he remains without a timetable for a return. Anthony, 22, has been out since early May, and although he has begun to take batting practice, there's still no clear timetable for his return to Boston.

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St. Louis Cardinals outfielder Jordan Walker (knee) will remain sidelined for Wednesday's tilt in the Bronx against the New York Yankees, per MLB.com. Jose Fermin will man right field and bat cleanup for the Cards against Yankees right-hander Will Warren. Walker will sit out a second straight game after he was scratched from the starting nine on Tuesday with inflammation in his right knee. Hopefully, it's nothing that keeps the right-handed slugging All-Star out for too much longer. The 24-year-old former top outfield prospect took a while to deliver on his power/speed potential, but he has finally come through in 2026, slashing .285/.343/.491 with an .834 OPS, 22 home runs, 81 RBI, 14 stolen bases, and 68 runs scored in 111 games and 432 plate appearances in a career year. Walker even won the Home Run Derby over Kyle Schwarber in his first All-Star experience. His underlying metrics support Walker's 2026 breakout as well, so if healthy, fantasy managers should expect more of the same the rest of the way.

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Baltimore Orioles right-handed reliever Yennier Cano is emerging as a potential option for saves in deeper leagues after picking up his second save of the season in Tuesday's 3-1 win over the visiting Los Angeles Angels at Camden Yards. Both relievers Rico Garcia and Andrew Kittredge worked before Cano in this one, with the 32-year-old veteran closing things out with a hit allowed, no walks, and two strikeouts in his inning of work. Right-hander Ryan Helsley (elbow) remains on the injured list, and the O's traded away right-hander Tyler Wells, who was the only Baltimore pitcher to have more than one save chance since the All-Star break in mid-July. Cano has been sharp this year, going 2-2 with a 2.09 ERA (2.37 FIP), 0.93 WHIP, two saves, 34 strikeouts, and only eight walks in 38 2/3 innings out of the bullpen in his fifth big-league season. He's been even better since the start of July, allowing just one earned run with one walk, seven strikeouts, a win, one save, one blown save, and two holds. Fantasy managers speculating on saves in deep leagues should look Cano's way. He's rostered in just 5% of Yahoo leagues.

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Arizona Diamondbacks right-hander Michael Soroka (lower body) made his first minor-league rehab start on Tuesday with Triple-A Reno and allowed an earned run on three hits while walking two and striking out one in four innings against Triple-A El Paso. The 29-year-old Canadian hurler will need one more rehab assignment, at the most, before the D-backs return him to their starting rotation for the stretch run. Fantasy managers who have been stashing Soroka (he's rostered in 66% of Yahoo leagues) are hoping that he can return to his pre-injury form from earlier this year. The former first-rounder by the Atlanta Braves in 2015 has had one of his best seasons in the big leagues in 2026 in his first year in the desert, going 8-3 with a 3.07 ERA (2.93 FIP) and 1.08 WHIP with 79 strikeouts and 17 walks in 82 frames across his 15 starts with the Snakes. Fantasy managers in deeper mixed leagues should consider stashing Soroka now.

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Los Angeles Dodgers manager Dave Roberts said that the team will have conversations about activating right-hander Tyler Glasnow (back) from the 60-day injured list once he makes two more minor-league rehab starts and builds up to four innings, per MLB.com's Sonja Chen. Glasnow kicked off his rehab assignment on Tuesday with Low-A Ontario and threw two shutout innings with one hit allowed, no walks, and one strikeout against Low-A Lake Elsinore. The 32-year-old hard-throwing right-hander looked just fine in the outing, but the Dodgers are slow-playing the former All-Star since he hasn't pitched in the majors since May 6 due to a lower-back injury. Even though Glasnow might only have around a month's worth of starts left in him in 2026 once he returns, he's rostered in nearly 90% of Yahoo leagues for his high-end strikeout upside on the best team in baseball. Before his back injury earlier this year, Glasnow was cruising along with a 3-0 record, 2.72 ERA (3.25 FIP) and 0.83 WHIP with 49 strikeouts and 13 walks in 39 2/3 innings across seven starts.

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Chicago Cubs right-handed reliever Daniel Palencia (elbow) will start a minor-league rehab assignment at Triple-A Iowa on Wednesday, according to Meghan Montemurro of The Chicago Tribune. Palencia has been sidelined since June 16 with a mild right flexor strain, but the 26-year-old is nearing a return to the major-league bullpen for the stretch run. Because of injuries in 2026, Palencia has only thrown 16 2/3 innings and recorded all three of his saves after picking up a career-high 22 saves in 54 regular-season appearances in 2025. The Cubs picked up right-handed reliever Ryan Zeferjahn from the Los Angeles Angels at Monday's trade deadline, but when back and fully healthy, Palencia is expected to take over as the team's primary closer in the ninth inning. Fantasy managers searching for saves should look to stash Palencia now. He's rostered in 59% of Yahoo leagues. Along with his three saves in 16 2/3 frames this year, Palencia has a 2.70 ERA (3.46 FIP), 1.38 WHIP, and 19:6 K:BB.

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Los Angeles Dodgers manager Dave Roberts said that while left-hander Blake Snell (elbow) didn't get into the fifth inning on Tuesday night in his fourth minor-league rehab start with Triple-A Oklahoma City, he did enough that his next start should be at the major-league level, according to Sonja Chen of MLB.com. Snell allowed three earned runs on five hits (two homers) while walking four and striking out three in 3 2/3 innings at OKC on Wednesday in what is believed to be his final rehab start before L.A. reinstates him from the 60-day injured list. The 33-year-old veteran and two-time Cy Young winner has made just one major-league start for the Blue in 2026 and has been sidelined since May 15 after having surgery to remove loose bodies from his elbow, but his high-strikeout upside has made him stash-worthy in fantasy all year. Now that he's on the verge of returning to the majors, he should be scooped up in the rest of the leagues where he's available. Although Snell threw 73 pitches on Tuesday, he'll be riskier as a fantasy starter initially, with the Dodgers likely easing him back into the rotation after his long layoff. His next start figures to come early next week against the Kansas City Royals.

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