CJ Abrams had three hits including a grand slam, Miles Mikolas pitched into the sixth inning and the host Washington Nationals routed the Minnesota Twins 15-2 on Wednesday night.

Brady House, Drew Millas and Jose Tena each had two hits including a home run for the Nationals, who collected 14 hits. Abrams also had two doubles and five RBIs, and James Wood and Jacob Young each had two hits.

Mikolas (1-3), signed as a free agent in the offseason, began the game with an 8.23 ERA. The right-hander pitched a season-high 5 1/3 innings, giving up two runs on three hits. Mikolas retired 16 of the 19 batters he faced to earn his first Washington win.

Three Washington pitchers held Minnesota to three hits. Matt Wallner had two hits including a home run for Minnesota, which had won two straight.

Twins starter Bailey Ober (3-2) went five-plus innings, allowing five runs on six hits.

Minnesota took a 1-0 lead in the third when Luke Keaschall doubled and scored on a Wallner single.

Washington did not get a baserunner against Ober until Wood singled leading off the fourth. Wood stole second with one out and Curtis Mead walked. Abrams followed with a double to score Wood.

Wallner homered off Mikolas in the fifth to put Twins up 2-1.

Young singled leading off the bottom half and Millas homered to center to give Washington a 3-2 lead.

In the sixth, back-to-back doubles by Abrams and House ended Ober's night. Tena greeted reliever Andrew Morris with Washington's third straight double to make it 5-2. With two outs, Nasim Nunez tripled to right and the lead was 6-2.

Daylen Lile walked leading off the bottom of the seventh and, with two outs, House homered to center to make it 8-2.

Young singled, Millas doubled and Wood singled them both home in the eighth. Washington loaded the bases and Abrams smacked a grand slam to right-center, the second of his career. Tena followed with a homer to make it 15-2.