Tyler Heineman's fielder's choice grounder in the bottom of the 10th scored the winning run and the Toronto Blue Jays came back to defeat the visiting Houston Astros 4-3 on Tuesday night.

Automatic runner Myles Straw took third on Vladimir Guerrero Jr.'s infield hit against Craig Kimbrel (0-1) and beat the throw home on Heineman's grounder to first. George Springer homered for the Blue Jays. Guerrero had three hits.

Toronto (83-61) tied the game in the ninth on Isiah Kiner-Falefa's two-run single. Toronto's Jeff Hoffman (9-6) pitched a clean 10th.

Carlos Correa hit a two-run home run for the Astros (78-67). Houston's Yordan Alvarez and Yainer Diaz each added three hits in the opener of a three-game series.

Red Sox 6, Athletics 0

Connelly Early struck out 11 to match the franchise record for a pitcher in his major league debut, tossing five shutout innings as Boston notched a victory over the Athletics in West Sacramento, Calif.

The 23-year-old left-hander, promoted from Triple-A Worcester earlier in the day, allowed five hits. Early (1-0) matched the team strikeout record set by Don Aase in his first start for Boston on July 26, 1977. Rob Refsnyder had a three-run homer among two hits and Romy Gonzalez added a homer, a double and two RBIs. Boston is in a virtual tie for second place with the New York Yankees in the American League, three games behind Toronto.

Jacob Wilson had three hits and Zach Gelof and Shea Langeliers had two apiece for the Athletics, who have been blanked in each of the first two games of this series. A's starter Jeffrey Springs (10-11) served up two first-inning homers and wound up yielding five runs and eight hits over five-plus innings.

Orioles 3, Pirates 2 (11 innings)

Samuel Basallo's bases-loaded single drove in the winning run and Baltimore topped visiting Pittsburgh in the opener of a three-game series.

It was Basallo's second walk-off hit in less than a week, as he also delivered a walk-off homer to beat the Dodgers on Aug. 5. Jeremiah Jackson also homered for the Orioles, who got seven strong innings from Kyle Bradish in his third start back from Tommy John surgery.

Pittsburgh's Tommy Pham hit a tying home run in the ninth, but the Pirates failed to score in each of their two extra-inning attempts. They have seven total runs in their last four games, all losses.

Guardians 2, Royals 0

Joey Cantillo and Cade Smith combined on a five-hit shutout and Jose Ramirez homered among his three hits as Cleveland beat visiting Kansas City.

Cantillo (5-3) was replaced by Smith after allowing a leadoff single to Kyle Isbel to begin the ninth inning. Ramirez came within a triple of hitting for the cycle for Cleveland, which won its fifth straight game and maintained its position in second place in the AL Central over the Royals. Cantillo allowed four hits over a career-high eight-plus innings.

Kansas City starter Noah Cameron (7-7) gave up two runs on six hits with eight strikeouts and no walks over seven innings.

Dodgers 7, Rockies 2

Emmet Sheehan took a no-hit bid into the sixth inning and Teoscar Hernandez hit a pair of home runs as Los Angeles earned a victory over visiting Colorado.

Sheehan (6-3) matched a career high by lasting seven innings. He allowed three hits and fanned nine. Freddie Freeman and Mookie Betts also homered for the Dodgers.

Hunter Goodman hit his 30th home run of the season for the Rockies. German Marquez (3-13) gave up five runs on six hits over five innings.

Cubs 6, Braves 1

Cade Horton baffled the Atlanta bats for the second straight outing with 6 1/3 strong innings and Pete Crow-Armstrong drove in a pair of runs to help visiting Chicago beat the Braves to even their three-game series.

The Cubs ended a three-game losing streak and now hold a 3-2 lead over the Braves in the season series. Horton (10-4) allowed one run on four hits. He threw 87 pitches and lowered his ERA to 2.70.

Atlanta's Spencer Strider (5-13) suffered his fifth straight loss. He pitched six innings and allowed two runs on six hits.

Nationals 7, Marlins 5

Josh Bell homered to highlight his four-RBI performance and Mitchell Parker tossed 7 2/3 strong innings to fuel Washington to a win over host Miami.

Bell belted a three-run homer to stake Washington to a 3-0 lead in the first. He added a sacrifice fly in the sixth for the Nationals, who have defeated the Marlins four times during their 7-1 run over the last eight games. Parker (8-15) allowed two runs on four hits to record his first win since July 26.

The Marlins made it interesting in the ninth. Victor Mesa Jr. ripped a two-run double with two outs and scored on Xavier Edwards' infield single. Jose Ferrer, however, induced Agustin Ramirez to ground out to secure his eighth save.

Giants 5, Diamondbacks 3

Willy Adames and Patrick Bailey hit home runs, Joel Peguero and Ryan Walker pitched out of late jams and San Francisco made it two straight over visiting Arizona.

Robbie Ray remained unbeaten against his former team with a third consecutive win, combining with four relievers on an eight-hitter as the Giants won for the 13th time in the past 16 games. San Francisco trails the New York Mets by two games for the final National League wild card. Matt Chapman added a double for the Giants, who had only five hits, three of which went for extra bases.

Seeking to end a two-game losing streak, the Diamondbacks got within 5-3 on an RBI single by Ildemaro Vargas off Giants reliever Matt Gage with one out in the sixth. Zac Gallen (11-14) yielded all five Giants runs on five hits in 6 2/3 innings.

Reds 4, Padres 2

Tyler Stephenson lined a two-run homer in the top of the ninth inning Tuesday night, snapping a tie and lifting visiting Cincinnati to a win over San Diego.

Gavin Lux drew a two-out walk off Robert Suarez (4-6) before Stephenson ripped his 10th homer of the year into the left field seats, enabling Cincinnati to pull within three games of the New York Mets for the National League's final wild-card spot. Connor Phillips (2-0) worked a scoreless eighth inning.

The Padres fell two games behind the first-place Los Angeles Dodgers in the NL West. San Diego right-hander Michael King made his first start in a month after being sidelined by left knee inflammation following his Aug. 9 start against Boston. He gave up three hits and two runs in five innings.

Tigers 12, Yankees 2

Parker Meadows hit a tying two-run homer in the fifth inning and a tiebreaking RBI single to spark a nine-run seventh inning as Detroit blew out New York.

Meadows snapped a 2-2 tie by lining a single to right field. In all, Yankees relievers Fernando Cruz (2-4), Mark Leiter Jr. and Tim Hill combined to allow nine runs on five hits to go along with five walks as the Tigers sent 14 to the plate. Detroit starter Casey Mize allowed two runs on six hits in six innings, striking out eight and walking none.

Aaron Judge hit his 359th homer off Detroit's Casey Mize (14-5) in the first inning to pass Yogi Berra for fifth on New York's all-time list. Cody Bellinger also homered, but the Yankees finished with four hits while taking their fourth loss in the past 15 games. New York starter Will Warren allowed two runs on two hits in six innings.

Phillies 9, Mets 3

Ranger Suarez struck out a career-high 12 batters and Kyle Schwarber hit his 50th homer as Philadelphia topped visiting New York.

Suarez (12-6) tossed six scoreless innings for the Phillies, allowing just a hit and three walks. Otto Kemp homered on his 26th birthday and Harrison Bader also went deep as part of a 3-for-5 night for the hosts. Schwarber's milestone home run made him just the second Phillie in franchise history to hit 50 in a season, joining Ryan Howard.

Mets starter Sean Manaea (1-3) was charged with four runs and five hits over five innings. Mark Vientos' home run highlighted a quiet night for the visitors.

Rangers 5, Brewers 4

Rookie Michael Helman hit a two-run home run and stole a homer at the fence to help surging Texas earn a come-from-behind win over Milwaukee in Arlington, Texas.

Hoby Milner (3-4), the second of six Texas pitchers, worked a scoreless inning to garner the victory. Shawn Armstrong allowed a solo home run to Jake Bauers in the ninth before recording his eighth save.

Brewers reliever Aaron Ashby (3-2) gave up two runs on four hits in 1 2/3 innings. Jackson Chourio led Milwaukee with three hits.

Rays 5, White Sox 4

Tristan Gray hit a go-ahead solo home run in the seventh inning and Josh Lowe and Richie Palacios also went deep as visiting Tampa Bay edged Chicago.

Junior Caminero lined a leadoff double in the second inning off White Sox starter Yoendrys Gomez and scored on Lowe's two-run blast. Gray, who spent most of the season with Triple-A Charlotte in the Chicago minor league system, struck against his former organization with his seventh-inning blast against Tyler Alexander (5-14). Former White Sox starter Adrian Houser scattered three runs and four hits in 5 1/3 innings with zero walks and a season-high nine strikeouts.

The White Sox grabbed a 1-0 lead on Kyle Teel's solo home run in the first inning. Chase Meidroth had an RBI single in the fifth and Colson Montgomery and Andrew Benintendi drove in runs in the sixth to tie the score. Gomez allowed four runs and five hits in five innings.

Mariners 5, Cardinals 3

Randy Arozarena homered and drove in four runs and Josh Naylor also went deep as Seattle defeated visiting St. Louis.

Five relievers combined for five scoreless innings of two-hit ball as the Mariners won their fourth in a row and pulled within a game of the division-leading Houston Astros in the American League West.

Caleb Ferguson (4-4) earned victory in relief, and Andres Munoz worked the ninth for his 34th save. Cardinals starter Matthew Liberatore (7-12) lasted four innings, allowing five runs on six hits. Jose Fermin had two hits and an RBI for St. Louis.

Angels 12, Twins 2

Kyle Hendricks scattered four hits over seven shutout innings and Chris Taylor and Yoan Moncada each hit three-run homers to lead Los Angeles to a victory over Minnesota in Anaheim, Calif.

Hendricks (7-9) walked one and struck out six while snapping a seven-start winless streak dating back to a 4-1 victory over Seattle on July 27. Moncada went 2-for-4 with a walk, three RBIs and three runs scored and Taylor finished 2-for-5 with four RBIs for the Angels, who finished with 17 hits and a season high in runs scored.

Ryan Fitzgerald, an infielder who came in to pitch a scoreless eighth, homered, Byron Buxton had two hits and stole a base and Austin Martin also had two hits and scored a run for Minnesota. Zebby Matthews (4-5) suffered the loss, allowing five runs on seven hits in 4 2/3 innings.